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A mouse model of Zhu-Tokita-Takenouchi-Kim syndrome reveals indispensable SON functions in organ development and hematopoiesis.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Sah JP, Lee SN, Stanford D, Barrington RA, Foote JB, Sorace AG, Welner RS, Hildreth BE 3rd, Lim SS, Ahn EE. Vukadin L, et al. Among authors: kim hg, kim jh. JCI Insight. 2024 Mar 8;9(5):e175053. doi: 10.1172/jci.insight.175053. JCI Insight. 2024. PMID: 38290089 Free PMC article.
A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Lee SN, Stanford D, Barrington RA, Foote JB, Sorace AG, Welner RS, Hildreth BE 3rd, Lim SS, Ahn EE. Vukadin L, et al. Among authors: kim hg, kim jh. bioRxiv [Preprint]. 2023 Nov 19:2023.11.19.567732. doi: 10.1101/2023.11.19.567732. bioRxiv. 2023. PMID: 38014320 Free PMC article. Updated. Preprint.
SON inhibits megakaryocytic differentiation via repressing RUNX1 and the megakaryocytic gene expression program in acute megakaryoblastic leukemia.
Vukadin L, Kim JH, Park EY, Stone JK, Ungerleider N, Baddoo MC, Kong HK, Richard A, Tran J, Giannini H, Flemington EK, Lim SS, Ahn EE. Vukadin L, et al. Among authors: kim jh. Cancer Gene Ther. 2021 Sep;28(9):1000-1015. doi: 10.1038/s41417-020-00262-9. Epub 2020 Nov 27. Cancer Gene Ther. 2021. PMID: 33247227 Free PMC article.
son is necessary for proper vertebrate blood development.
Belmonte RL, Engbretson IL, Kim JH, Cajias I, Ahn EE, Stachura DL. Belmonte RL, et al. Among authors: kim jh. PLoS One. 2021 Feb 25;16(2):e0247489. doi: 10.1371/journal.pone.0247489. eCollection 2021. PLoS One. 2021. PMID: 33630943 Free PMC article.
Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription.
Jeong K, Kim JH, Murphy JM, Park H, Kim SJ, Rodriguez YAR, Kong H, Choi C, Guan JL, Taylor JM, Lincoln TM, Gerthoffer WT, Kim JS, Ahn EE, Schlaepfer DD, Lim SS. Jeong K, et al. Among authors: kim sj, kim js, kim jh. Circ Res. 2019 Jul 5;125(2):152-166. doi: 10.1161/CIRCRESAHA.118.314344. Epub 2019 May 17. Circ Res. 2019. PMID: 31096851 Free PMC article.
FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes.
Jeong K, Murphy JM, Kim JH, Campbell PM, Park H, Rodriguez YAR, Choi CS, Kim JS, Park S, Kim HJ, Scammell JG, Weber DS, Honkanen RE, Schlaepfer DD, Ahn EE, Lim SS. Jeong K, et al. Among authors: kim hj, kim js, kim jh. Circ Res. 2021 Dec 3;129(12):e215-e233. doi: 10.1161/CIRCRESAHA.121.319066. Epub 2021 Oct 27. Circ Res. 2021. PMID: 34702049 Free PMC article.
SON haploinsufficiency causes impaired pre-mRNA splicing of CAKUT genes and heterogeneous renal phenotypes.
Kim JH, Park EY, Chitayat D, Stachura DL, Schaper J, Lindstrom K, Jewett T, Wieczorek D, Draaisma JM, Sinnema M, Hoeberigs C, Hempel M, Bachman KK, Seeley AH, Stone JK, Kong HK, Vukadin L, Richard A, Shinde DN, McWalter K, Si YC, Douglas G, Lim ST, Vissers LELM, Lemaire M, Ahn EE. Kim JH, et al. Kidney Int. 2019 Jun;95(6):1494-1504. doi: 10.1016/j.kint.2019.01.025. Epub 2019 Mar 15. Kidney Int. 2019. PMID: 31005274 Free PMC article.
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