Sleebs BE - Search Results

1

Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity.

Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Nie S, Williamson N, Zheng Y, Young ND, Korhonen PK, Hofmann A, Chang BCH, Wells TNC, Häberli C, Keiser J, Jabbar A, Sleebs BE, Gasser RB. Shanley HT, et al. Among authors: sleebs be. Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100522. doi: 10.1016/j.ijpddr.2024.100522. Epub 2024 Jan 23. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38295619 Free PMC article.

2

An appraisal of natural products active against parasitic nematodes of animals.

Garcia-Bustos JF, Sleebs BE, Gasser RB. Garcia-Bustos JF, et al. Among authors: sleebs be. Parasit Vectors. 2019 Jun 17;12(1):306. doi: 10.1186/s13071-019-3537-1. Parasit Vectors. 2019. PMID: 31208455 Free PMC article. Review.

3

Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro.

Herath HMPD, Taki AC, Nguyen N, Garcia-Bustos J, Hofmann A, Wang T, Ma G, Chang BCH, Jabbar A, Sleebs BE, Gasser RB. Herath HMPD, et al. Among authors: sleebs be. Molecules. 2020 Apr 24;25(8):2004. doi: 10.3390/molecules25082004. Molecules. 2020. PMID: 32344703 Free PMC article.

4

Development and application of a high-throughput screening assay for identification of small molecule inhibitors of the P. falciparum reticulocyte binding-like homologue 5 protein.

Sleebs BE, Jarman KE, Frolich S, Wong W, Healer J, Dai W, Lucet IS, Wilson DW, Cowman AF. Sleebs BE, et al. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:188-200. doi: 10.1016/j.ijpddr.2020.10.008. Epub 2020 Oct 29. Int J Parasitol Drugs Drug Resist. 2020. PMID: 33152623 Free PMC article.

5

Advances in the discovery and development of anthelmintics by harnessing natural product scaffolds.

Herath HMPD, Taki AC, Sleebs BE, Hofmann A, Nguyen N, Preston S, Davis RA, Jabbar A, Gasser RB. Herath HMPD, et al. Among authors: sleebs be. Adv Parasitol. 2021;111:203-251. doi: 10.1016/bs.apar.2020.10.002. Epub 2021 Jan 8. Adv Parasitol. 2021. PMID: 33482975 Review.

6

Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2.

Nguyen W, Lee EF, Evangelista M, Lee M, Harris TJ, Colman PM, Smith NA, Williams LB, Jarman KE, Lowes KN, Haeberli C, Keiser J, Smith BJ, Fairlie WD, Sleebs BE. Nguyen W, et al. Among authors: sleebs be. ACS Infect Dis. 2021 May 14;7(5):1143-1163. doi: 10.1021/acsinfecdis.0c00700. Epub 2021 Feb 1. ACS Infect Dis. 2021. PMID: 33523649

7

Late Stage Phosphotyrosine Mimetic Functionalization of Peptides Employing Metallaphotoredox Catalysis.

Chen H, Mao R, Brzozowski M, Nguyen NH, Sleebs BE. Chen H, et al. Among authors: sleebs be. Org Lett. 2021 Jun 4;23(11):4244-4249. doi: 10.1021/acs.orglett.1c01200. Epub 2021 May 24. Org Lett. 2021. PMID: 34029466

8

Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro.

Taki AC, Jabbar A, Kurz T, Lungerich B, Ma G, Byrne JJ, Pflieger M, Asfaha Y, Fischer F, Chang BCH, Sleebs BE, Gasser RB. Taki AC, et al. Among authors: sleebs be. Molecules. 2021 May 10;26(9):2819. doi: 10.3390/molecules26092819. Molecules. 2021. PMID: 34068691 Free PMC article.

9

High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus.

Taki AC, Byrne JJ, Wang T, Sleebs BE, Nguyen N, Hall RS, Korhonen PK, Chang BCH, Jackson P, Jabbar A, Gasser RB. Taki AC, et al. Among authors: sleebs be. Pharmaceuticals (Basel). 2021 Jun 26;14(7):616. doi: 10.3390/ph14070616. Pharmaceuticals (Basel). 2021. PMID: 34206910 Free PMC article.

10

A High-Throughput Phenotypic Screen of the 'Pandemic Response Box' Identifies a Quinoline Derivative with Significant Anthelmintic Activity.

Shanley HT, Taki AC, Byrne JJ, Jabbar A, Wells TNC, Samby K, Boag PR, Nguyen N, Sleebs BE, Gasser RB. Shanley HT, et al. Among authors: sleebs be. Pharmaceuticals (Basel). 2022 Feb 21;15(2):257. doi: 10.3390/ph15020257. Pharmaceuticals (Basel). 2022. PMID: 35215369 Free PMC article.

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