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Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model.
Rossano SM, Johnson AS, Smith A, Ziaggi G, Roetman A, Guzman D, Okafor A, Klein J, Tomljanovic Z, Stern Y, Brickman AM, Lee S, Kreisl WC, Lao P. Rossano SM, et al. Among authors: lao p. Alzheimers Dement. 2024 Apr;20(4):2397-2407. doi: 10.1002/alz.13699. Epub 2024 Feb 1. Alzheimers Dement. 2024. PMID: 38298155 Free PMC article.
Tract-defined regional white matter hyperintensities and memory.
Rizvi B, Lao PJ, Colón J, Hale C, Igwe KC, Narkhede A, Budge M, Manly JJ, Schupf N, Brickman AM. Rizvi B, et al. Neuroimage Clin. 2020;25:102143. doi: 10.1016/j.nicl.2019.102143. Epub 2019 Dec 23. Neuroimage Clin. 2020. PMID: 31887716 Free PMC article.
Further understanding the connection between Alzheimer's disease and Down syndrome.
Snyder HM, Bain LJ, Brickman AM, Carrillo MC, Esbensen AJ, Espinosa JM, Fernandez F, Fortea J, Hartley SL, Head E, Hendrix J, Kishnani PS, Lai F, Lao P, Lemere C, Mobley W, Mufson EJ, Potter H, Zaman SH, Granholm AC, Rosas HD, Strydom A, Whitten MS, Rafii MS. Snyder HM, et al. Among authors: lao p. Alzheimers Dement. 2020 Jul;16(7):1065-1077. doi: 10.1002/alz.12112. Epub 2020 Jun 16. Alzheimers Dement. 2020. PMID: 32544310 Free PMC article. Review.
Alzheimer-Related Cerebrovascular Disease in Down Syndrome.
Lao PJ, Gutierrez J, Keator D, Rizvi B, Banerjee A, Igwe KC, Laing KK, Sathishkumar M, Moni F, Andrews H, Krinsky-McHale S, Head E, Lee JH, Lai F, Yassa MA, Rosas HD, Silverman W, Lott IT, Schupf N, Brickman AM. Lao PJ, et al. Ann Neurol. 2020 Dec;88(6):1165-1177. doi: 10.1002/ana.25905. Epub 2020 Oct 9. Ann Neurol. 2020. PMID: 32944999 Free PMC article.
84 results