Sullivan DK - Search Results

1

Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma.

Deutzmann A, Sullivan DK, Dhanasekaran R, Li W, Chen X, Tong L, Mahauad-Fernandez WD, Bell J, Mosley A, Koehler AN, Li Y, Felsher DW. Deutzmann A, et al. Among authors: sullivan dk. Nat Commun. 2024 Feb 1;15(1):963. doi: 10.1038/s41467-024-45128-y. Nat Commun. 2024. PMID: 38302473 Free PMC article.

2

Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma.

Gouw AM, Eberlin LS, Margulis K, Sullivan DK, Toal GG, Tong L, Zare RN, Felsher DW. Gouw AM, et al. Among authors: sullivan dk. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4300-4305. doi: 10.1073/pnas.1617709114. Epub 2017 Apr 11. Proc Natl Acad Sci U S A. 2017. PMID: 28400509 Free PMC article.

3

The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth.

Gouw AM, Margulis K, Liu NS, Raman SJ, Mancuso A, Toal GG, Tong L, Mosley A, Hsieh AL, Sullivan DK, Stine ZE, Altman BJ, Schulze A, Dang CV, Zare RN, Felsher DW. Gouw AM, et al. Among authors: sullivan dk. Cell Metab. 2019 Sep 3;30(3):556-572.e5. doi: 10.1016/j.cmet.2019.07.012. Epub 2019 Aug 22. Cell Metab. 2019. PMID: 31447321 Free PMC article.

4

Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.

Du R, Sullivan DK, Azizian NG, Liu Y, Li Y. Du R, et al. Among authors: sullivan dk. BMC Cancer. 2021 Mar 6;21(1):237. doi: 10.1186/s12885-021-07967-6. BMC Cancer. 2021. PMID: 33676427 Free PMC article.

5

MYC oncogene elicits tumorigenesis associated with embryonic, ribosomal biogenesis, and tissue-lineage dedifferentiation gene expression changes.

Sullivan DK, Deutzmann A, Yarbrough J, Krishnan MS, Gouw AM, Bellovin DI, Adam SJ, Liefwalker DF, Dhanasekaran R, Felsher DW. Sullivan DK, et al. Oncogene. 2022 Nov;41(45):4960-4970. doi: 10.1038/s41388-022-02458-9. Epub 2022 Oct 7. Oncogene. 2022. PMID: 36207533 Free PMC article.

6

mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.

Liu Y, Azizian NG, Sullivan DK, Li Y. Liu Y, et al. Among authors: sullivan dk. Nat Commun. 2022 Nov 17;13(1):7047. doi: 10.1038/s41467-022-34890-6. Nat Commun. 2022. PMID: 36396656 Free PMC article.

7

MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint.

Smith BAH, Deutzmann A, Correa KM, Delaveris CS, Dhanasekaran R, Dove CG, Sullivan DK, Wisnovsky S, Stark JC, Pluvinage JV, Swaminathan S, Riley NM, Rajan A, Majeti R, Felsher DW, Bertozzi CR. Smith BAH, et al. Among authors: sullivan dk. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2215376120. doi: 10.1073/pnas.2215376120. Epub 2023 Mar 10. Proc Natl Acad Sci U S A. 2023. PMID: 36897988 Free PMC article.

8

Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo.

Azizian NG, Sullivan DK, Nie L, Pardo S, Molleur D, Chen J, Weintraub ST, Li Y. Azizian NG, et al. Among authors: sullivan dk. J Proteome Res. 2021 Jan 1;20(1):858-866. doi: 10.1021/acs.jproteome.0c00666. Epub 2020 Dec 8. J Proteome Res. 2021. PMID: 33289385 Free PMC article.

9

Genome organization around nuclear speckles drives mRNA splicing efficiency.

Bhat P, Chow A, Emert B, Ettlin O, Quinodoz SA, Strehle M, Takei Y, Burr A, Goronzy IN, Chen AW, Huang W, Ferrer JLM, Soehalim E, Goh ST, Chari T, Sullivan DK, Blanco MR, Guttman M. Bhat P, et al. Among authors: sullivan dk. Nature. 2024 May;629(8014):1165-1173. doi: 10.1038/s41586-024-07429-6. Epub 2024 May 8. Nature. 2024. PMID: 38720076

10

ClinicNet: machine learning for personalized clinical order set recommendations.

Wang JX, Sullivan DK, Wells AC, Chen JH. Wang JX, et al. Among authors: sullivan dk. JAMIA Open. 2020 Jun 28;3(2):216-224. doi: 10.1093/jamiaopen/ooaa021. eCollection 2020 Jul. JAMIA Open. 2020. PMID: 32734162 Free PMC article.

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