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Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores.
Kappel DB, Legge SE, Hubbard L, Willcocks IR, O'Connell KS, Smith RL, Molden E, Andreassen OA, King A, Jansen J, Helthuis M, Owen MJ, O'Donovan MC, Walters JTR, Pardiñas AF. Kappel DB, et al. Among authors: jansen j. Biol Psychiatry. 2023 Jan 15;93(2):149-156. doi: 10.1016/j.biopsych.2022.07.014. Epub 2022 Aug 5. Biol Psychiatry. 2023. PMID: 36244804 Free PMC article.
A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia.
Legge SE, Pardiñas AF, Helthuis M, Jansen JA, Jollie K, Knapper S, MacCabe JH, Rujescu D, Collier DA, O'Donovan MC, Owen MJ, Walters JTR. Legge SE, et al. Among authors: jansen ja. Mol Psychiatry. 2019 Mar;24(3):328-337. doi: 10.1038/s41380-018-0335-7. Epub 2019 Jan 15. Mol Psychiatry. 2019. PMID: 30647433
Pharmacokinetics and pharmacogenomics of clozapine in an ancestrally diverse sample: a longitudinal analysis and genome-wide association study using UK clinical monitoring data.
Pardiñas AF, Kappel DB, Roberts M, Tipple F, Shitomi-Jones LM, King A, Jansen J, Helthuis M, Owen MJ, O'Donovan MC, Walters JTR. Pardiñas AF, et al. Among authors: jansen j. Lancet Psychiatry. 2023 Mar;10(3):209-219. doi: 10.1016/S2215-0366(23)00002-0. Lancet Psychiatry. 2023. PMID: 36804072 Free PMC article.
Using natural language processing for automated classification of disease and to identify misclassified ICD codes in cardiac disease.
Falter M, Godderis D, Scherrenberg M, Kizilkilic SE, Xu L, Mertens M, Jansen J, Legroux P, Kindermans H, Sinnaeve P, Neven F, Dendale P. Falter M, et al. Among authors: jansen j. Eur Heart J Digit Health. 2024 Feb 9;5(3):229-234. doi: 10.1093/ehjdh/ztae008. eCollection 2024 May. Eur Heart J Digit Health. 2024. PMID: 38774372 Free PMC article.
4,034 results