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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria.
Watson FN, Shears MJ, Kalata AC, Duncombe CJ, Seilie AM, Chavtur C, Conrad E, Cruz Talavera I, Raappana A, Sather DN, Chakravarty S, Sim BKL, Hoffman SL, Tsuji M, Murphy SC. Watson FN, et al. Among authors: murphy sc. Sci Rep. 2024 Feb 4;14(1):2881. doi: 10.1038/s41598-024-53118-9. Sci Rep. 2024. PMID: 38311678 Free PMC article.
Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies.
Hodgson SH, Douglas AD, Edwards NJ, Kimani D, Elias SC, Chang M, Daza G, Seilie AM, Magiri C, Muia A, Juma EA, Cole AO, Rampling TW, Anagnostou NA, Gilbert SC, Hoffman SL, Draper SJ, Bejon P, Ogutu B, Marsh K, Hill AV, Murphy SC. Hodgson SH, et al. Among authors: murphy sc. Malar J. 2015 Jan 28;14:33. doi: 10.1186/s12936-015-0541-6. Malar J. 2015. PMID: 25627033 Free PMC article.
Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects.
Kublin JG, Mikolajczak SA, Sack BK, Fishbaugher ME, Seilie A, Shelton L, VonGoedert T, Firat M, Magee S, Fritzen E, Betz W, Kain HS, Dankwa DA, Steel RW, Vaughan AM, Noah Sather D, Murphy SC, Kappe SH. Kublin JG, et al. Among authors: murphy sc. Sci Transl Med. 2017 Jan 4;9(371):eaad9099. doi: 10.1126/scitranslmed.aad9099. Sci Transl Med. 2017. PMID: 28053159 Clinical Trial.
Multiplex, DNase-free one-step reverse transcription PCR for Plasmodium 18S rRNA and spliced gametocyte-specific mRNAs.
Hanron AE, Billman ZP, Seilie AM, Olsen TM, Fishbaugher M, Chang M, Rueckle T, Andenmatten N, Greenhouse B, Arinaitwe E, Rek J, Das S, Domingo GJ, Shipman K, Kappe SH, Kublin JG, Murphy SC. Hanron AE, et al. Among authors: murphy sc. Malar J. 2017 May 19;16(1):208. doi: 10.1186/s12936-017-1863-3. Malar J. 2017. PMID: 28526032 Free PMC article.
Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice.
Sack BK, Mikolajczak SA, Fishbaugher M, Vaughan AM, Flannery EL, Nguyen T, Betz W, Jane Navarro M, Foquet L, Steel RWJ, Billman ZP, Murphy SC, Hoffman SL, Chakravarty S, Sim BKL, Behet M, Reuling IJ, Walk J, Scholzen A, Sauerwein RW, Ishizuka AS, Flynn B, Seder RA, Kappe SHI. Sack BK, et al. Among authors: murphy sc. NPJ Vaccines. 2017 Oct 9;2:27. doi: 10.1038/s41541-017-0028-2. eCollection 2017. NPJ Vaccines. 2017. PMID: 29263882 Free PMC article.
158 results