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A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings.
Véniant MM, Lu SC, Atangan L, Komorowski R, Stanislaus S, Cheng Y, Wu B, Falsey JR, Hager T, Thomas VA, Ambhaikar M, Sharpsten L, Zhu Y, Kurra V, Jeswani R, Oberoi RK, Parnes JR, Honarpour N, Neutel J, Strande JL. Véniant MM, et al. Among authors: strande jl. Nat Metab. 2024 Feb;6(2):290-303. doi: 10.1038/s42255-023-00966-w. Epub 2024 Feb 5. Nat Metab. 2024. PMID: 38316982 Free PMC article. Clinical Trial.
Identification of Cardiac Fibrosis in Young Adults With a Homozygous Frameshift Variant in SERPINE1.
Khan SS, Shah SJ, Strande JL, Baldridge AS, Flevaris P, Puckelwartz MJ, McNally EM, Rasmussen-Torvik LJ, Lee DC, Carr JC, Benefield BC, Afzal MZ, Heiman M, Gupta S, Shapiro AD, Vaughan DE. Khan SS, et al. Among authors: strande jl. JAMA Cardiol. 2021 Jul 1;6(7):841-846. doi: 10.1001/jamacardio.2020.6909. JAMA Cardiol. 2021. PMID: 33439236 Free PMC article.
A Pilot Study of Cardiac MRI in Breast Cancer Survivors After Cardiotoxic Chemotherapy and Three-Dimensional Conformal Radiotherapy.
Bergom C, Rubenstein J, Wilson JF, Welsh A, Ibrahim EH, Prior P, Schottstaedt AM, Eastwood D, Zhang MJ, Currey A, Puckett L, Strande JL, Bradley JA, White J. Bergom C, et al. Among authors: strande jl. Front Oncol. 2020 Oct 16;10:506739. doi: 10.3389/fonc.2020.506739. eCollection 2020. Front Oncol. 2020. PMID: 33178571 Free PMC article.
Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart.
Thirugnanam K, Cossette SM, Lu Q, Chowdhury SR, Harmann LM, Gupta A, Spearman AD, Sonin DL, Bordas M, Kumar SN, Pan AY, Simpson PM, Strande JL, Bishop E, Zou MH, Ramchandran R. Thirugnanam K, et al. Among authors: strande jl. J Am Heart Assoc. 2019 Nov 19;8(22):e012792. doi: 10.1161/JAHA.119.012792. Epub 2019 Nov 13. J Am Heart Assoc. 2019. PMID: 31718444 Free PMC article.
46 results