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Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα.
Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C, Navas CR, Gordillo R, Neinast M, Kalainayakan SP, Li DL, Gao Y, Yi CX, Hahner L, Palmer BF, Tschöp MH, Clegg DJ. Morselli E, et al. Among authors: gao y. Cell Rep. 2014 Oct 23;9(2):633-45. doi: 10.1016/j.celrep.2014.09.025. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373903 Free PMC article.
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH. García-Cáceres C, et al. Among authors: gao y. Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028. Cell. 2016. PMID: 27518562 Free PMC article.
TNFα drives mitochondrial stress in POMC neurons in obesity.
Yi CX, Walter M, Gao Y, Pitra S, Legutko B, Kälin S, Layritz C, García-Cáceres C, Bielohuby M, Bidlingmaier M, Woods SC, Ghanem A, Conzelmann KK, Stern JE, Jastroch M, Tschöp MH. Yi CX, et al. Among authors: gao y. Nat Commun. 2017 May 10;8:15143. doi: 10.1038/ncomms15143. Nat Commun. 2017. PMID: 28489068 Free PMC article.
Dietary sugars, not lipids, drive hypothalamic inflammation.
Gao Y, Bielohuby M, Fleming T, Grabner GF, Foppen E, Bernhard W, Guzmán-Ruiz M, Layritz C, Legutko B, Zinser E, García-Cáceres C, Buijs RM, Woods SC, Kalsbeek A, Seeley RJ, Nawroth PP, Bidlingmaier M, Tschöp MH, Yi CX. Gao Y, et al. Mol Metab. 2017 Jun 20;6(8):897-908. doi: 10.1016/j.molmet.2017.06.008. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752053 Free PMC article.
Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity.
Gao Y, Vidal-Itriago A, Kalsbeek MJ, Layritz C, García-Cáceres C, Tom RZ, Eichmann TO, Vaz FM, Houtkooper RH, van der Wel N, Verhoeven AJ, Yan J, Kalsbeek A, Eckel RH, Hofmann SM, Yi CX. Gao Y, et al. Cell Rep. 2017 Sep 26;20(13):3034-3042. doi: 10.1016/j.celrep.2017.09.008. Cell Rep. 2017. PMID: 28954222 Free article.
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