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Bile salt hydrolase catalyses formation of amine-conjugated bile acids.
Rimal B, Collins SL, Tanes CE, Rocha ER, Granda MA, Solanki S, Hoque NJ, Gentry EC, Koo I, Reilly ER, Hao F, Paudel D, Singh V, Yan T, Kim MS, Bittinger K, Zackular JP, Krausz KW, Desai D, Amin S, Coleman JP, Shah YM, Bisanz JE, Gonzalez FJ, Vanden Heuvel JP, Wu GD, Zemel BS, Dorrestein PC, Weinert EE, Patterson AD. Rimal B, et al. Among authors: gonzalez fj. Nature. 2024 Feb;626(8000):859-863. doi: 10.1038/s41586-023-06990-w. Epub 2024 Feb 7. Nature. 2024. PMID: 38326609 Free PMC article.
Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer.
Sun L, Zhang Y, Cai J, Rimal B, Rocha ER, Coleman JP, Zhang C, Nichols RG, Luo Y, Kim B, Chen Y, Krausz KW, Harris CC, Patterson AD, Zhang Z, Takahashi S, Gonzalez FJ. Sun L, et al. Among authors: gonzalez fj. Nat Commun. 2023 Feb 10;14(1):755. doi: 10.1038/s41467-023-36089-9. Nat Commun. 2023. PMID: 36765047 Free PMC article.
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.
Sun L, Xie C, Wang G, Wu Y, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C. Sun L, et al. Among authors: gonzalez fj. Nat Med. 2018 Dec;24(12):1919-1929. doi: 10.1038/s41591-018-0222-4. Epub 2018 Nov 5. Nat Med. 2018. PMID: 30397356 Free PMC article.
Reverse metabolomics for the discovery of chemical structures from humans.
Gentry EC, Collins SL, Panitchpakdi M, Belda-Ferre P, Stewart AK, Carrillo Terrazas M, Lu HH, Zuffa S, Yan T, Avila-Pacheco J, Plichta DR, Aron AT, Wang M, Jarmusch AK, Hao F, Syrkin-Nikolau M, Vlamakis H, Ananthakrishnan AN, Boland BS, Hemperly A, Vande Casteele N, Gonzalez FJ, Clish CB, Xavier RJ, Chu H, Baker ES, Patterson AD, Knight R, Siegel D, Dorrestein PC. Gentry EC, et al. Among authors: gonzalez fj. Nature. 2024 Feb;626(7998):419-426. doi: 10.1038/s41586-023-06906-8. Epub 2023 Dec 5. Nature. 2024. PMID: 38052229 Free PMC article.
1,507 results