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DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Daily KP, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan MH, Carafice C, Krause K, McNamara A, Hamilton K, Houle S, Gupta S, Gupta GA, Madhu S, Fitzgerald J, Saadey AA, Laster B, Yan P, Webb A, Zhang X, Pietrzak M, Kokiko-Cochran ON, Ghoneim HE, Amer AO. Daily KP, et al. Among authors: kokiko cochran on. Alzheimers Res Ther. 2024 Feb 8;16(1):29. doi: 10.1186/s13195-024-01390-2. Alzheimers Res Ther. 2024. PMID: 38326859 Free PMC article.
Robust Transcriptional Profiling and Identification of Differentially Expressed Genes With Low Input RNA Sequencing of Adult Hippocampal Neural Stem and Progenitor Populations.
Denninger JK, Walker LA, Chen X, Turkoglu A, Pan A, Tapp Z, Senthilvelan S, Rindani R, Kokiko-Cochran ON, Bundschuh R, Yan P, Kirby ED. Denninger JK, et al. Front Mol Neurosci. 2022 Jan 31;15:810722. doi: 10.3389/fnmol.2022.810722. eCollection 2022. Front Mol Neurosci. 2022. PMID: 35173579 Free PMC article.
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates neuroinflammation and amyloid-β deposition in Alzheimer's disease The Ohio State University College of Medicine.
Daily KP, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan MH, Carafice C, Krause K, McNamara A, Hamilton K, Houle S, Gupta S, Gupta GA, Madhu S, Fitzgerald J, Saadey AA, Laster B, Yan P, Webb A, Zhang X, Pietrzak M, Kokiko-Cochran ON, Ghoneim HE, Amer AO. Daily KP, et al. Among authors: kokiko cochran on. bioRxiv [Preprint]. 2023 Sep 1:2023.08.30.555526. doi: 10.1101/2023.08.30.555526. bioRxiv. 2023. PMID: 37693600 Free PMC article. Preprint.
Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease.
Badr A, Daily KP, Eltobgy M, Estfanous S, Tan MH, Chun-Tien Kuo J, Whitham O, Carafice C, Gupta G, Amer HM, Shamseldin MM, Yousif A, Deems NP, Fitzgerald J, Yan P, Webb A, Zhang X, Pietrzak M, Ghoneim HE, Dubey P, Barrientos RM, Lee RJ, Kokiko-Cochran ON, Amer AO. Badr A, et al. Among authors: kokiko cochran on. Brain Behav Immun. 2024 May 7;119:919-944. doi: 10.1016/j.bbi.2024.05.006. Online ahead of print. Brain Behav Immun. 2024. PMID: 38718909 Free article.
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, Wemlinger T, Wu M, Kokiko-Cochran ON, Popovich P, Flowers XE, Honig LS, Vonsattel JP, Scharre DW, Beach TG, Ma Q, Kuret J, Kõks S, Urano F, Duff KE, Fu H. Chen S, et al. Acta Neuropathol. 2022 May;143(5):547-569. doi: 10.1007/s00401-022-02417-4. Epub 2022 Apr 7. Acta Neuropathol. 2022. PMID: 35389045
43 results