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Mannose-coupled AAV2: A second-generation AAV vector for increased retinal gene therapy efficiency.
Mével M, Pichard V, Bouzelha M, Alvarez-Dorta D, Lalys PA, Provost N, Allais M, Mendes A, Landagaray E, Ducloyer JB, Toublanc E, Galy A, Brument N, Lefevre GM, Gouin SG, Isiegas C, Le Meur G, Cronin T, Le Guiner C, Weber M, Moullier P, Ayuso E, Deniaud D, Adjali O. Mével M, et al. Among authors: ayuso e. Mol Ther Methods Clin Dev. 2024 Jan 17;32(1):101187. doi: 10.1016/j.omtm.2024.101187. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38327809 Free PMC article.
Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina.
Leray A, Lalys PA, Varin J, Bouzelha M, Bourdon A, Alvarez-Dorta D, Pavageau K, Depienne S, Marchand M, Mellet A, Demilly J, Ducloyer JB, Girard T, Fraysse B, Ledevin M, Guilbaud M, Gouin SG, Ayuso E, Adjali O, Larcher T, Cronin T, Le Guiner C, Deniaud D, Mével M. Leray A, et al. Among authors: ayuso e. Biomed Pharmacother. 2024 Feb;171:116148. doi: 10.1016/j.biopha.2024.116148. Epub 2024 Jan 16. Biomed Pharmacother. 2024. PMID: 38232661 Free article.
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells.
Ferrari S, Jacob A, Cesana D, Laugel M, Beretta S, Varesi A, Unali G, Conti A, Canarutto D, Albano L, Calabria A, Vavassori V, Cipriani C, Castiello MC, Esposito S, Brombin C, Cugnata F, Adjali O, Ayuso E, Merelli I, Villa A, Di Micco R, Kajaste-Rudnitski A, Montini E, Penaud-Budloo M, Naldini L. Ferrari S, et al. Among authors: ayuso e. Cell Stem Cell. 2022 Oct 6;29(10):1428-1444.e9. doi: 10.1016/j.stem.2022.09.001. Cell Stem Cell. 2022. PMID: 36206730 Free PMC article.
Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates.
Milani M, Canepari C, Liu T, Biffi M, Russo F, Plati T, Curto R, Patarroyo-White S, Drager D, Visigalli I, Brombin C, Albertini P, Follenzi A, Ayuso E, Mueller C, Annoni A, Naldini L, Cantore A. Milani M, et al. Among authors: ayuso e. Nat Commun. 2022 May 4;13(1):2454. doi: 10.1038/s41467-022-30102-3. Nat Commun. 2022. PMID: 35508619 Free PMC article.
Baboon Envelope Pseudotyped "Nanoblades" Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells.
Gutierrez-Guerrero A, Abrey Recalde MJ, Mangeot PE, Costa C, Bernadin O, Périan S, Fusil F, Froment G, Martinez-Turtos A, Krug A, Martin F, Benabdellah K, Ricci EP, Giovannozzi S, Gijsbers R, Ayuso E, Cosset FL, Verhoeyen E. Gutierrez-Guerrero A, et al. Among authors: ayuso e. Front Genome Ed. 2021 Feb 9;3:604371. doi: 10.3389/fgeed.2021.604371. eCollection 2021. Front Genome Ed. 2021. PMID: 34713246 Free PMC article.
Do Age and Sex Influence Anorectal Manometry Parameters?
Jutras G, Wahba G, Ayuso E, Neshkova E, Bouin M. Jutras G, et al. Among authors: ayuso e. J Can Assoc Gastroenterol. 2021 Apr 23;4(5):235-241. doi: 10.1093/jcag/gwaa045. eCollection 2021 Oct. J Can Assoc Gastroenterol. 2021. PMID: 34617005 Free PMC article.
Homologous Recombination Offers Advantages over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production.
Jacob A, Brun L, Jiménez Gil P, Ménard L, Bouzelha M, Broucque F, Roblin A, Vandenberghe LH, Adjali O, Robin C, François A, Blouin V, Penaud-Budloo M, Ayuso E. Jacob A, et al. Among authors: ayuso e. Biotechnol J. 2021 Jan;16(1):e2000014. doi: 10.1002/biot.202000014. Epub 2020 Nov 16. Biotechnol J. 2021. PMID: 33067902
62 results