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Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study.
Neurology. 2024 Mar 12;102(5):e209151. doi: 10.1212/WNL.0000000000209151. Epub 2024 Feb 8.
Neurology. 2024.
PMID: 38330285
Free PMC article.
Clinical Trial.
A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy.
Barrett D, Bilic S, Chyung Y, Cote SM, Iarrobino R, Kacena K, Kalra A, Long K, Nomikos G, Place A, Still JG, Vrishabhendra L.
Barrett D, et al. Among authors: iarrobino r.
Adv Ther. 2021 Jun;38(6):3203-3222. doi: 10.1007/s12325-021-01757-z. Epub 2021 May 8.
Adv Ther. 2021.
PMID: 33963971
Free PMC article.
Clinical Trial.
Item in Clipboard
Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis.
Banerji A, Busse P, Shennak M, Lumry W, Davis-Lorton M, Wedner HJ, Jacobs J, Baker J, Bernstein JA, Lockey R, Li HH, Craig T, Cicardi M, Riedl M, Al-Ghazawi A, Soo C, Iarrobino R, Sexton DJ, TenHoor C, Kenniston JA, Faucette R, Still JG, Kushner H, Mensah R, Stevens C, Biedenkapp JC, Chyung Y, Adelman B.
Banerji A, et al. Among authors: iarrobino r.
N Engl J Med. 2017 Feb 23;376(8):717-728. doi: 10.1056/NEJMoa1605767.
N Engl J Med. 2017.
PMID: 28225674
Free article.
Clinical Trial.
Item in Clipboard
Ecallantide for the acute treatment of angiotensin-converting enzyme inhibitor-induced angioedema: a multicenter, randomized, controlled trial.
Lewis LM, Graffeo C, Crosley P, Klausner HA, Clark CL, Frank A, Miner J, Iarrobino R, Chyung Y.
Lewis LM, et al. Among authors: iarrobino r.
Ann Emerg Med. 2015 Feb;65(2):204-13. doi: 10.1016/j.annemergmed.2014.07.014. Epub 2014 Aug 30.
Ann Emerg Med. 2015.
PMID: 25182544
Clinical Trial.
Item in Clipboard
A phase 1 study investigating DX-2930 in healthy subjects.
Chyung Y, Vince B, Iarrobino R, Sexton D, Kenniston J, Faucette R, TenHoor C, Stolz LE, Stevens C, Biedenkapp J, Adelman B.
Chyung Y, et al. Among authors: iarrobino r.
Ann Allergy Asthma Immunol. 2014 Oct;113(4):460-6.e2. doi: 10.1016/j.anai.2014.05.028. Epub 2014 Jun 26.
Ann Allergy Asthma Immunol. 2014.
PMID: 24980392
Free article.
Clinical Trial.
Item in Clipboard
Efficacy and safety of ecallantide in treatment of recurrent attacks of hereditary angioedema: open-label continuation study.
Lumry WR, Bernstein JA, Li HH, MacGinnitie AJ, Riedl M, Soteres DF, Craig TJ, Campion M, Iarrobino R, Stolz LE, Pullman WE.
Lumry WR, et al. Among authors: iarrobino r.
Allergy Asthma Proc. 2013 Mar-Apr;34(2):155-61. doi: 10.2500/aap.2013.34.3653.
Allergy Asthma Proc. 2013.
PMID: 23484891
Clinical Trial.
Item in Clipboard
Assessment of rebound and relapse following ecallantide treatment for acute attacks of hereditary angioedema.
Bernstein JA, Shea EP, Koester J, Iarrobino R, Pullman WE.
Bernstein JA, et al. Among authors: iarrobino r.
Allergy. 2012 Sep;67(9):1173-80. doi: 10.1111/j.1398-9995.2012.02864.x. Epub 2012 Jul 5.
Allergy. 2012.
PMID: 22765833
Clinical Trial.
Item in Clipboard
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