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aProceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH).
Tapias EA, Miles DM, Albillos A, Aller R, Ampuero J, Andrade R, Arechederra M, Aspichueta P, Banales JM, García AB, Caparros E, Delgado TC, Vico AC, Claria J, Cubero FJ, Ruiz AD, Fernández-Barrena MG, Iglesias AF, Veledo SF, Francés R, Durán RG, Sancho JG, Irimia M, Lens S, Martínez-Chantar ML, Mínguez B, Hernández RM, Nogueiras R, Molina BR, Barciela MR, Rodríguez-Perálvarez ML, Gómez MR, Sabio G, Bru PS, Cots MV, Vidal S, Gahete MD. Tapias EA, et al. Among authors: aspichueta p. Gastroenterol Hepatol. 2024 May 7:502207. doi: 10.1016/j.gastrohep.2024.502207. Online ahead of print. Gastroenterol Hepatol. 2024. PMID: 38723772 Free article. English, Spanish.
The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis.
Ampuero J, Aller R, Gallego-Durán R, Crespo J, Calleja JL, García-Monzón C, Gómez-Camarero J, Caballería J, Lo Iacono O, Ibañez L, García-Samaniego J, Albillos A, Francés R, Fernández-Rodríguez C, Maya-Miles D, Diago M, Poca M, Andrade RJ, Latorre R, Jorquera F, Morillas RM, Escudero D, Hernández-Guerra M, Pareja-Megia MJ, Banales JM, Aspichueta P, Benlloch S, Rosales JM, Turnes J, Romero-Gómez M; HEPAmet Registry. Ampuero J, et al. Among authors: aspichueta p. J Gastroenterol. 2024 Apr 15. doi: 10.1007/s00535-024-02098-8. Online ahead of print. J Gastroenterol. 2024. PMID: 38619600
A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes.
Saliba-Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk-Maczynska E, Li J, Najmi LA, Apodaka M, Aspichueta P, Björck HM, Eriksson P, Franco-Cereceda A, Gloudemans M, Mujica E, den Hoed M, Assimes TL, Quertermous T, Carcamo-Orive I, Park CY, Knowles JW. Saliba-Gustafsson P, et al. Among authors: aspichueta p. medRxiv [Preprint]. 2024 Feb 4:2024.02.03.24302258. doi: 10.1101/2024.02.03.24302258. medRxiv. 2024. PMID: 38352379 Free PMC article. Preprint.
Thyroid hormone receptor alpha modulates fibrogenesis in hepatic stellate cells.
Manka P, Coombes JD, Sydor S, Swiderska-Syn MK, Best J, Gauthier K, van Grunsven LA, Oo YH, Wang C, Diehl AM, Hönes GS, Moeller LC, Figge A, Boosman RJ, Faber KN, Tannapfel A, Goetze O, Aspichueta P, Lange CM, Canbay A, Syn WK. Manka P, et al. Among authors: aspichueta p. Liver Int. 2024 Jan;44(1):125-138. doi: 10.1111/liv.15759. Epub 2023 Oct 23. Liver Int. 2024. PMID: 37872645
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting.
Capelo-Diz A, Lachiondo-Ortega S, Fernández-Ramos D, Cañas-Martín J, Goikoetxea-Usandizaga N, Serrano-Maciá M, González-Rellan MJ, Mosca L, Blazquez-Vicens J, Tinahones-Ruano A, Fondevila MF, Buyan M, Delgado TC, Gutierrez de Juan V, Ayuso-García P, Sánchez-Rueda A, Velasco-Avilés S, Fernández-Susavila H, Riobello-Suárez C, Dziechciarz B, Montiel-Duarte C, Lopitz-Otsoa F, Bizkarguenaga M, Bilbao-García J, Bernardo-Seisdedos G, Senra A, Soriano-Navarro M, Millet O, Díaz-Lagares Á, Crujeiras AB, Bao-Caamano A, Cabrera D, van Liempd S, Tamayo-Carro M, Borzacchiello L, Gomez-Santos B, Buqué X, Sáenz de Urturi D, González-Romero F, Simon J, Rodríguez-Agudo R, Ruiz A, Matute C, Beiroa D, Falcon-Perez JM, Aspichueta P, Rodríguez-Cuesta J, Porcelli M, Pajares MA, Ameneiro C, Fidalgo M, Aransay AM, Lama-Díaz T, Blanco MG, López M, Villa-Bellosta R, Müller TD, Nogueiras R, Woodhoo A, Martínez-Chantar ML, Varela-Rey M. Capelo-Diz A, et al. Among authors: aspichueta p. Cell Metab. 2023 Aug 8;35(8):1373-1389.e8. doi: 10.1016/j.cmet.2023.07.002. Epub 2023 Jul 31. Cell Metab. 2023. PMID: 37527658 Free PMC article.
Serum identification of at-risk MASH: The metabolomics-advanced steatohepatitis fibrosis score (MASEF).
Noureddin M, Truong E, Mayo R, Martínez-Arranz I, Mincholé I, Banales JM, Arrese M, Cusi K, Arias-Loste MT, Bruha R, Romero-Gómez M, Iruzubieta P, Aller R, Ampuero J, Calleja JL, Ibañez-Samaniego L, Aspichueta P, Martín-Duce A, Kushner T, Ortiz P, Harrison SA, Anstee QM, Crespo J, Mato JM, Sanyal AJ. Noureddin M, et al. Among authors: aspichueta p. Hepatology. 2024 Jan 1;79(1):135-148. doi: 10.1097/HEP.0000000000000542. Epub 2023 Jul 24. Hepatology. 2024. PMID: 37505221 Free PMC article.
Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S. Marsal-Beltran A, et al. Among authors: aspichueta p. Metabolism. 2023 Aug;145:155630. doi: 10.1016/j.metabol.2023.155630. Epub 2023 Jun 13. Metabolism. 2023. PMID: 37315889 Free article.
In Vivo Tissue Lipid Uptake in Antisense Oligonucleotide (ASO)-Treated Mice.
Aurrekoetxea I, Gomez-Santos B, Apodaka-Biguri M, Ruiz de Gauna M, Gonzalez-Romero F, Buqué X, Aspichueta P. Aurrekoetxea I, et al. Among authors: aspichueta p. Methods Mol Biol. 2023;2675:1-13. doi: 10.1007/978-1-0716-3247-5_1. Methods Mol Biol. 2023. PMID: 37258751
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