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Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
ACS Med Chem Lett. 2024 Jan 8;15(2):181-188. doi: 10.1021/acsmedchemlett.3c00455. eCollection 2024 Feb 8.
ACS Med Chem Lett. 2024.
PMID: 38352830
Promoting Catalytic C-Selective Sulfonylation of Cyclopropanols against Conventional O-Sulfonylation Using Readily Available Sulfonyl Chlorides.
Ramar T, Ilangovan A, A M Subbaiah M.
Ramar T, et al. Among authors: a m subbaiah m.
J Org Chem. 2023 Oct 6;88(19):13553-13567. doi: 10.1021/acs.joc.3c01230. Epub 2023 Sep 14.
J Org Chem. 2023.
PMID: 37708032
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Improving Drug Delivery While Tailoring Prodrug Activation to Modulate Cmax and Cmin by Optimization of (Carbonyl)oxyalkyl Linker-Based Prodrugs of Atazanavir.
A M Subbaiah M, Subramani L, Ramar T, Desai S, Sinha S, Mandlekar S, Kadow JF, Jenkins S, Krystal M, Subramanian M, Sridhar S, Padmanabhan S, Bhutani P, Arla R, Meanwell NA.
A M Subbaiah M, et al.
J Med Chem. 2022 Aug 25;65(16):11150-11176. doi: 10.1021/acs.jmedchem.2c00632. Epub 2022 Aug 11.
J Med Chem. 2022.
PMID: 35952307
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The Ligand Free Palladium(II)-Catalyzed Regioselective 1,2-Addition of Enol Silanes to Quinones to Access 4-Hydroxy-4-(2-oxo-2-arylethyl)cyclohexadien-1-ones and Synthetic Applications.
Polimera SR, A M Subbaiah M, Ilangovan A.
Polimera SR, et al. Among authors: a m subbaiah m.
J Org Chem. 2021 Nov 5;86(21):14356-14370. doi: 10.1021/acs.joc.1c00857. Epub 2021 Sep 23.
J Org Chem. 2021.
PMID: 34554740
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Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir.
A M Subbaiah M, Mandlekar S, Desikan S, Ramar T, Subramani L, Annadurai M, Desai SD, Sinha S, Jenkins SM, Krystal MR, Subramanian M, Sridhar S, Padmanabhan S, Bhutani P, Arla R, Singh S, Sinha J, Thakur M, Kadow JF, Meanwell NA.
A M Subbaiah M, et al.
J Med Chem. 2019 Apr 11;62(7):3553-3574. doi: 10.1021/acs.jmedchem.9b00002. Epub 2019 Apr 2.
J Med Chem. 2019.
PMID: 30938524
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