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Page 1
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
Poudel YB, He L, Cox M, Zhang Q, Johnson WL, Cong Q, Cheng H, Chowdari NS, Tarby C, Donnell AF, Broekema M, O'Malley DP, Zhang Y, A M Subbaiah M, Kumar BV, Subramani L, Wang B, Li YX, Sivaprakasam P, Critton D, Mulligan D, Sandhu B, Xie C, Ramakrishnan R, Nagar J, Dudhgaonkar S, Oderinde MS, Murtaza A, Schieven GL, Mathur A, Gavai AV, Vite G, Gangwar S. Poudel YB, et al. Among authors: chowdari ns. ACS Med Chem Lett. 2024 Jan 8;15(2):181-188. doi: 10.1021/acsmedchemlett.3c00455. eCollection 2024 Feb 8. ACS Med Chem Lett. 2024. PMID: 38352830
DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody-Drug Conjugate Modality.
Sivaprakasam P, McDonald I, Iwuagwu C, Chowdari NS, Peese KM, Langley DR, Cheng H, Luzung MR, Schmidt MA, Zheng B, Tan Y, Cho P, Rakshit S, Lakshminarasimhan T, Guturi S, Kanagavel K, Kanusu U, Niyogi AG, Sidhar S, Vaidyanathan R, Eastgate MD, Kotapati S, Deshpande M, Pan C, Cardarelli PM, Xie C, Rao C, Holder P, Sarma G, Vite G, Gangwar S. Sivaprakasam P, et al. Among authors: chowdari ns. ACS Med Chem Lett. 2021 Feb 10;12(3):404-412. doi: 10.1021/acsmedchemlett.0c00578. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33738068 Free PMC article.
Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates.
Chowdari NS, Zhang Y, McDonald I, Johnson W, Langley DR, Sivaprakasam P, Mate R, Huynh T, Kotapati S, Deshpande M, Pan C, Menezes D, Wang Y, Rao C, Sarma G, Warrack BM, Rangan VS, Mei-Chen S, Cardarelli P, Deshpande S, Passmore D, Rampulla R, Mathur A, Borzilleri R, Rajpal A, Vite G, Gangwar S. Chowdari NS, et al. J Med Chem. 2020 Nov 25;63(22):13913-13950. doi: 10.1021/acs.jmedchem.0c01385. Epub 2020 Nov 6. J Med Chem. 2020. PMID: 33155811
Total Synthesis of Meayamycin and O-Acyl Analogues.
Gartshore C, Tadano S, Chanda PB, Sarkar A, Chowdari NS, Gangwar S, Zhang Q, Vite GD, Momirov J, Boger DL. Gartshore C, et al. Among authors: chowdari ns. Org Lett. 2020 Nov 6;22(21):8714-8719. doi: 10.1021/acs.orglett.0c03308. Epub 2020 Oct 19. Org Lett. 2020. PMID: 33074680 Free PMC article.
Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies.
Kotapati S, Passmore D, Yamazoe S, Sanku RKK, Cong Q, Poudel YB, Chowdari NS, Gangwar S, Rao C, Rangan VS, Cardarelli PM, Deshpande S, Strop P, Dollinger G, Rajpal A. Kotapati S, et al. Among authors: chowdari ns. Anal Chem. 2020 Jan 21;92(2):2065-2073. doi: 10.1021/acs.analchem.9b04572. Epub 2020 Jan 6. Anal Chem. 2020. PMID: 31860282
Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations.
Nicolaou KC, Wang Y, Lu M, Mandal D, Pattanayak MR, Yu R, Shah AA, Chen JS, Zhang H, Crawford JJ, Pasunoori L, Poudel YB, Chowdari NS, Pan C, Nazeer A, Gangwar S, Vite G, Pitsinos EN. Nicolaou KC, et al. Among authors: chowdari ns. J Am Chem Soc. 2016 Jul 6;138(26):8235-46. doi: 10.1021/jacs.6b04339. Epub 2016 Jun 27. J Am Chem Soc. 2016. PMID: 27266267
21 results