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Page 1
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
Poudel YB, He L, Cox M, Zhang Q, Johnson WL, Cong Q, Cheng H, Chowdari NS, Tarby C, Donnell AF, Broekema M, O'Malley DP, Zhang Y, A M Subbaiah M, Kumar BV, Subramani L, Wang B, Li YX, Sivaprakasam P, Critton D, Mulligan D, Sandhu B, Xie C, Ramakrishnan R, Nagar J, Dudhgaonkar S, Oderinde MS, Murtaza A, Schieven GL, Mathur A, Gavai AV, Vite G, Gangwar S. Poudel YB, et al. Among authors: mulligan d. ACS Med Chem Lett. 2024 Jan 8;15(2):181-188. doi: 10.1021/acsmedchemlett.3c00455. eCollection 2024 Feb 8. ACS Med Chem Lett. 2024. PMID: 38352830
Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology.
He L, Zhang MY, Cox M, Zhang Q, Donnell AF, Zhang Y, Tarby C, Gill P, Subbaiah MAM, Ramar T, Reddy M, Puttapaka V, Li YX, Sivaprakasam P, Critton D, Mulligan D, Xie C, Ramakrishnan R, Nagar J, Dudhgaonkar S, Murtaza A, Oderinde MS, Schieven GL, Mathur A, Gavai AV, Vite G, Gangwar S, Poudel YB. He L, et al. Among authors: mulligan d. ACS Med Chem Lett. 2024 Jan 9;15(2):189-196. doi: 10.1021/acsmedchemlett.3c00456. eCollection 2024 Feb 8. ACS Med Chem Lett. 2024. PMID: 38352849
Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2).
Moslin R, Zhang Y, Wrobleski ST, Lin S, Mertzman M, Spergel S, Tokarski JS, Strnad J, Gillooly K, McIntyre KW, Zupa-Fernandez A, Cheng L, Sun H, Chaudhry C, Huang C, D'Arienzo C, Heimrich E, Yang X, Muckelbauer JK, Chang C, Tredup J, Mulligan D, Xie D, Aranibar N, Chiney M, Burke JR, Lombardo L, Carter PH, Weinstein DS. Moslin R, et al. Among authors: mulligan d, d arienzo c. J Med Chem. 2019 Oct 24;62(20):8953-8972. doi: 10.1021/acs.jmedchem.9b00443. Epub 2019 Jul 17. J Med Chem. 2019. PMID: 31314518
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.
Wrobleski ST, Moslin R, Lin S, Zhang Y, Spergel S, Kempson J, Tokarski JS, Strnad J, Zupa-Fernandez A, Cheng L, Shuster D, Gillooly K, Yang X, Heimrich E, McIntyre KW, Chaudhry C, Khan J, Ruzanov M, Tredup J, Mulligan D, Xie D, Sun H, Huang C, D'Arienzo C, Aranibar N, Chiney M, Chimalakonda A, Pitts WJ, Lombardo L, Carter PH, Burke JR, Weinstein DS. Wrobleski ST, et al. Among authors: mulligan d, d arienzo c. J Med Chem. 2019 Oct 24;62(20):8973-8995. doi: 10.1021/acs.jmedchem.9b00444. Epub 2019 Jul 18. J Med Chem. 2019. PMID: 31318208
Liver Transplant Costs and Activity After United Network for Organ Sharing Allocation Policy Changes.
Ahmed O, Doyle MBM, Abouljoud MS, Alonso D, Batra R, Brayman KL, Brockmeier D, Cannon RM, Chavin K, Delman AM, DuBay DA, Finn J, Fridell JA, Friedman BS, Fritze DM, Ginos D, Goldberg DS, Halff GA, Karp SJ, Kohli VK, Kumer SC, Langnas A, Locke JE, Maluf D, Meier RPH, Mejia A, Merani S, Mulligan DC, Nibuhanupudy B, Patel MS, Pelletier SJ, Shah SA, Vagefi PA, Vianna R, Zibari GB, Shafer TJ, Orloff SL. Ahmed O, et al. Among authors: mulligan dc. JAMA Surg. 2024 May 29:e241208. doi: 10.1001/jamasurg.2024.1208. Online ahead of print. JAMA Surg. 2024. PMID: 38809546
Current Status of Liver Transplantation in North America.
Aziz H, Nayak P, Mulligan DC. Aziz H, et al. Among authors: mulligan dc. Surg Clin North Am. 2024 Feb;104(1):1-9. doi: 10.1016/j.suc.2023.08.002. Epub 2023 Sep 9. Surg Clin North Am. 2024. PMID: 37953028 Review.
Establishing the core elements of a frailty at the front door model of care using a modified real-time Delphi technique.
O'Shaughnessy Í, Fitzgerald C, Whiston A, Harnett P, Whitty H, Mulligan D, Mullaney M, Devaney C, Lang D, Hardimann J, Condon B, Hayes C, Holmes A, Barry L, McCormack C, Bounds M, Robinson K, O'Connor M, Ryan D, Shchetkovsky D, Steed F, Carey L, Ahern E, Galvin R. O'Shaughnessy Í, et al. Among authors: mulligan d. BMC Emerg Med. 2023 Oct 20;23(1):123. doi: 10.1186/s12873-023-00893-9. BMC Emerg Med. 2023. PMID: 37858041 Free PMC article.
New Allocation Systems: Principles and Processes (Pro).
Deshpande R, Shah R, Mulligan DC. Deshpande R, et al. Among authors: mulligan dc. Transplantation. 2023 Nov 1;107(11):2298-2301. doi: 10.1097/TP.0000000000004786. Epub 2023 Aug 30. Transplantation. 2023. PMID: 37644663 No abstract available.
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification.
Pardo-Palacios FJ, Wang D, Reese F, Diekhans M, Carbonell-Sala S, Williams B, Loveland JE, De María M, Adams MS, Balderrama-Gutierrez G, Behera AK, Gonzalez JM, Hunt T, Lagarde J, Liang CE, Li H, Jerryd Meade M, Moraga Amador DA, Prjibelski AD, Birol I, Bostan H, Brooks AM, Hasan Çelik M, Chen Y, Du MRM, Felton C, Göke J, Hafezqorani S, Herwig R, Kawaji H, Lee J, Liang Li J, Lienhard M, Mikheenko A, Mulligan D, Ming Nip K, Pertea M, Ritchie ME, Sim AD, Tang AD, Kei Wan Y, Wang C, Wong BY, Yang C, Barnes I, Berry A, Capella S, Dhillon N, Fernandez-Gonzalez JM, Ferrández-Peral L, Garcia-Reyero N, Goetz S, Hernández-Ferrer C, Kondratova L, Liu T, Martinez-Martin A, Menor C, Mestre-Tomás J, Mudge JM, Panayotova NG, Paniagua A, Repchevsky D, Rouchka E, Saint-John B, Sapena E, Sheynkman L, Laird Smith M, Suner MM, Takahashi H, Youngworth IA, Carninci P, Denslow ND, Guigó R, Hunter ME, Tilgner HU, Wold BJ, Vollmers C, Frankish A, Fai Au K, Sheynkman GM, Mortazavi A, Conesa A, Brooks AN. Pardo-Palacios FJ, et al. Among authors: mulligan d. bioRxiv [Preprint]. 2023 Jul 27:2023.07.25.550582. doi: 10.1101/2023.07.25.550582. bioRxiv. 2023. PMID: 37546854 Free PMC article. Preprint.
236 results