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Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis.
Astuti Y, Raymant M, Quaranta V, Clarke K, Abudula M, Smith O, Bellomo G, Chandran-Gorner V, Nourse C, Halloran C, Ghaneh P, Palmer D, Jones RP, Campbell F, Pollard JW, Morton JP, Mielgo A, Schmid MC. Astuti Y, et al. Among authors: schmid mc. Nat Cancer. 2024 May;5(5):774-790. doi: 10.1038/s43018-024-00731-2. Epub 2024 Feb 14. Nat Cancer. 2024. PMID: 38355776
UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis.
Abu-Alainin W, Gana T, Liloglou T, Olayanju A, Barrera LN, Ferguson R, Campbell F, Andrews T, Goldring C, Kitteringham N, Park BK, Nedjadi T, Schmid MC, Slupsky JR, Greenhalf W, Neoptolemos JP, Costello E. Abu-Alainin W, et al. Among authors: schmid mc. J Pathol. 2016 Feb;238(3):423-33. doi: 10.1002/path.4665. Epub 2015 Nov 30. J Pathol. 2016. PMID: 26497117 Free PMC article.
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
Nielsen SR, Quaranta V, Linford A, Emeagi P, Rainer C, Santos A, Ireland L, Sakai T, Sakai K, Kim YS, Engle D, Campbell F, Palmer D, Ko JH, Tuveson DA, Hirsch E, Mielgo A, Schmid MC. Nielsen SR, et al. Among authors: schmid mc. Nat Cell Biol. 2016 May;18(5):549-60. doi: 10.1038/ncb3340. Epub 2016 Apr 18. Nat Cell Biol. 2016. PMID: 27088855 Free PMC article.
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
Ireland L, Santos A, Ahmed MS, Rainer C, Nielsen SR, Quaranta V, Weyer-Czernilofsky U, Engle DD, Perez-Mancera PA, Coupland SE, Taktak A, Bogenrieder T, Tuveson DA, Campbell F, Schmid MC, Mielgo A. Ireland L, et al. Among authors: schmid mc. Cancer Res. 2016 Dec 1;76(23):6851-6863. doi: 10.1158/0008-5472.CAN-16-1201. Epub 2016 Oct 14. Cancer Res. 2016. PMID: 27742686 Free PMC article.
Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma.
Figueiredo CR, Azevedo RA, Mousdell S, Resende-Lara PT, Ireland L, Santos A, Girola N, Cunha RLOR, Schmid MC, Polonelli L, Travassos LR, Mielgo A. Figueiredo CR, et al. Among authors: schmid mc. Front Immunol. 2018 May 23;9:1132. doi: 10.3389/fimmu.2018.01132. eCollection 2018. Front Immunol. 2018. PMID: 29875777 Free PMC article.
122 results