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Page 1
Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease.
Shoffner-Beck SK, Abernathy-Close L, Lazar S, Ma F, Gharaee-Kermani M, Hurst A, Dobry C, Pandian D, Wasikowski R, Victory A, Arnold K, Gudjonsson JE, Tsoi LC, Kahlenberg JM. Shoffner-Beck SK, et al. Among authors: gharaee kermani m. JCI Insight. 2024 Feb 15;9(6):e173437. doi: 10.1172/jci.insight.173437. JCI Insight. 2024. PMID: 38358820 Free PMC article.
HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling.
Uppala R, Sarkar MK, Young KZ, Ma F, Vemulapalli P, Wasikowski R, Plazyo O, Swindell WR, Maverakis E, Gharaee-Kermani M, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE. Uppala R, et al. Among authors: gharaee kermani m. iScience. 2024 Jan 23;27(2):108986. doi: 10.1016/j.isci.2024.108986. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327798 Free PMC article.
Oral Baricitinib in the Treatment of Cutaneous Lichen Planus.
Hwang A, Kechter J, Do T, Hughes A, Zhang N, Li X, Wasikowski R, Brumfiel C, Patel M, Boudreaux B, Bhullar P, Nassir S, Yousif M, DiCaudo DJ, Fox J, Gharaee-Kermani M, Xing X, Zunich S, Branch E, Kahlenberg JM, Billi AC, Plazyo O, Tsoi LC, Pittelkow MR, Gudjonsson JE, Mangold AR. Hwang A, et al. Among authors: gharaee kermani m. medRxiv [Preprint]. 2024 Jan 11:2024.01.09.24300946. doi: 10.1101/2024.01.09.24300946. medRxiv. 2024. PMID: 38260663 Free PMC article. Preprint.
Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity.
Klein B, Reynolds MB, Xu B, Gharaee-Kermani M, Gao Y, Berthier CC, Henning S, Loftus SN, McNeely KE, Victory AM, Dobry C, Hile GA, Ma F, Turnier JL, Gudjonsson JE, O'Riordan MX, Kahlenberg JM. Klein B, et al. Among authors: gharaee kermani m. bioRxiv [Preprint]. 2024 Jan 26:2024.01.23.576771. doi: 10.1101/2024.01.23.576771. bioRxiv. 2024. PMID: 38328232 Free PMC article. Preprint.
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Ma F, et al. Among authors: gharaee kermani m. Nat Commun. 2024 Jan 3;15(1):210. doi: 10.1038/s41467-023-44645-6. Nat Commun. 2024. PMID: 38172207 Free PMC article.
Integrated omics analysis unveils a DNA damage response to neurogenic injury.
Gheinani AH, Sack BS, Bigger-Allen A, Thaker H, Atta H, Lambrinos G, Costa K, Doyle C, Gharaee-Kermani M, Patalano S, Piper M, Cotellessa JF, Vitko D, Li H, Prabhakaran MK, Cristofaro V, Froehlich J, Lee RS, Yang W, Sullivan MP, Macoska JA, Adam RM. Gheinani AH, et al. Among authors: gharaee kermani m. bioRxiv [Preprint]. 2023 Dec 10:2023.12.10.571015. doi: 10.1101/2023.12.10.571015. bioRxiv. 2023. PMID: 38106029 Free PMC article. Preprint.
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. van Straalen KR, et al. Among authors: gharaee kermani m. J Clin Invest. 2024 Feb 1;134(3):e169225. doi: 10.1172/JCI169225. J Clin Invest. 2024. PMID: 38051587 Free PMC article.
Single-cell profiling of prurigo nodularis demonstrates immune-stromal crosstalk driving profibrotic responses and reversal with nemolizumab.
Ma F, Gharaee-Kermani M, Tsoi LC, Plazyo O, Chaskar P, Harms P, Patrick MT, Xing X, Hile G, Piketty C, Lazzari A, Van Delm W, Maverakis E, Nakamura M, Modlin RL, Kahlenberg JM, Billi AC, Julia V, Krishnaswamy JK, Gudjonsson JE. Ma F, et al. Among authors: gharaee kermani m. J Allergy Clin Immunol. 2024 Jan;153(1):146-160. doi: 10.1016/j.jaci.2023.07.005. Epub 2023 Jul 26. J Allergy Clin Immunol. 2024. PMID: 37506977 Free article.
Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis.
Xing E, Ma F, Wasikowski R, Billi AC, Gharaee-Kermani M, Fox J, Dobry C, Victory A, Sarkar MK, Xing X, Plazyo O, Chen HW, Barber G, Jacobe H, Tsou PS, Modlin RL, Varga J, Kahlenberg JM, Tsoi LC, Gudjonsson JE, Khanna D. Xing E, et al. Among authors: gharaee kermani m. JCI Insight. 2023 Aug 22;8(16):e171307. doi: 10.1172/jci.insight.171307. JCI Insight. 2023. PMID: 37471168 Free PMC article.
62 results