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Early deficits in an in vitro striatal microcircuit model carrying the Parkinson's GBA-N370S mutation.
Do QB, Noor H, Marquez-Gomez R, Cramb KML, Ng B, Abbey A, Ibarra-Aizpurua N, Caiazza MC, Sharifi P, Lang C, Beccano-Kelly D, Baleriola J, Bengoa-Vergniory N, Wade-Martins R. Do QB, et al. Among authors: bengoa vergniory n. NPJ Parkinsons Dis. 2024 Apr 12;10(1):82. doi: 10.1038/s41531-024-00694-2. NPJ Parkinsons Dis. 2024. PMID: 38609392 Free PMC article.
Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Among authors: bengoa vergniory n. Mol Psychiatry. 2024 Feb 15. doi: 10.1038/s41380-024-02463-2. Online ahead of print. Mol Psychiatry. 2024. PMID: 38361127
Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons.
Beccano-Kelly DA, Cherubini M, Mousba Y, Cramb KML, Giussani S, Caiazza MC, Rai P, Vingill S, Bengoa-Vergniory N, Ng B, Corda G, Banerjee A, Vowles J, Cowley S, Wade-Martins R. Beccano-Kelly DA, et al. Among authors: bengoa vergniory n. iScience. 2023 Jun 7;26(7):107044. doi: 10.1016/j.isci.2023.107044. eCollection 2023 Jul 21. iScience. 2023. PMID: 37426342 Free PMC article.
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
Emmenegger M, De Cecco E, Hruska-Plochan M, Eninger T, Schneider MM, Barth M, Tantardini E, de Rossi P, Bacioglu M, Langston RG, Kaganovich A, Bengoa-Vergniory N, Gonzalez-Guerra A, Avar M, Heinzer D, Reimann R, Häsler LM, Herling TW, Matharu NS, Landeck N, Luk K, Melki R, Kahle PJ, Hornemann S, Knowles TPJ, Cookson MR, Polymenidou M, Jucker M, Aguzzi A. Emmenegger M, et al. Among authors: bengoa vergniory n. EMBO Mol Med. 2021 Sep 7;13(9):e14745. doi: 10.15252/emmm.202114745. Epub 2021 Jul 26. EMBO Mol Med. 2021. PMID: 34309222 Free PMC article.
Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol.
Threlfell S, Mohammadi AS, Ryan BJ, Connor-Robson N, Platt NJ, Anand R, Serres F, Sharp T, Bengoa-Vergniory N, Wade-Martins R, Ewing A, Cragg SJ, Brimblecombe KR. Threlfell S, et al. Among authors: bengoa vergniory n. Front Cell Neurosci. 2021 Apr 15;15:658244. doi: 10.3389/fncel.2021.658244. eCollection 2021. Front Cell Neurosci. 2021. PMID: 33935654 Free PMC article.
REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model.
Ryan BJ, Bengoa-Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, Sloan M, Saqlain S, Cherubini M, Poppinga J, Bogtofte H, Cioroch M, Hester S, Wade-Martins R. Ryan BJ, et al. Among authors: bengoa vergniory n. J Neurosci. 2021 Apr 21;41(16):3731-3746. doi: 10.1523/JNEUROSCI.1478-20.2021. Epub 2021 Feb 9. J Neurosci. 2021. PMID: 33563726 Free PMC article.
30 results