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Page 1
Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Among authors: bertherat f. Mol Psychiatry. 2024 Feb 15. doi: 10.1038/s41380-024-02463-2. Online ahead of print. Mol Psychiatry. 2024. PMID: 38361127
A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward.
Sakloth F, Sanchez-Reyes OB, Ruiz A, Nicolais A, Serafini RA, Pryce KD, Bertherat F, Torres-Berrío A, Gomes I, Devi LA, Wacker D, Zachariou V. Sakloth F, et al. Among authors: bertherat f. Mol Pharmacol. 2023 Jan;103(1):1-8. doi: 10.1124/molpharm.122.000528. Epub 2022 Oct 30. Mol Pharmacol. 2023. PMID: 36310031 Free PMC article.
FOXR1 regulates stress response pathways and is necessary for proper brain development.
Mota A, Waxman HK, Hong R, Lagani GD, Niu SY, Bertherat FL, Wolfe L, Malicdan CM, Markello TC, Adams DR, Gahl WA, Cheng CS, Beffert U, Ho A. Mota A, et al. Among authors: bertherat fl. PLoS Genet. 2021 Nov 1;17(11):e1009854. doi: 10.1371/journal.pgen.1009854. eCollection 2021 Nov. PLoS Genet. 2021. PMID: 34723967 Free PMC article.
A promising chemical series of positive allosteric modulators of the μ-opioid receptor that enhance the antinociceptive efficacy of opioids but not their adverse effects.
Pryce KD, Kang HJ, Sakloth F, Liu Y, Khan S, Toth K, Kapoor A, Nicolais A, Che T, Qin L, Bertherat F, Kaniskan HÜ, Jin J, Cameron MD, Roth BL, Zachariou V, Filizola M. Pryce KD, et al. Among authors: bertherat f. Neuropharmacology. 2021 Sep 1;195:108673. doi: 10.1016/j.neuropharm.2021.108673. Epub 2021 Jun 18. Neuropharmacology. 2021. PMID: 34153316 Free PMC article.
Regulators of G Protein Signaling in Analgesia and Addiction.
Sakloth F, Polizu C, Bertherat F, Zachariou V. Sakloth F, et al. Among authors: bertherat f. Mol Pharmacol. 2020 Dec;98(6):739-750. doi: 10.1124/mol.119.119206. Epub 2020 May 30. Mol Pharmacol. 2020. PMID: 32474445 Free PMC article. Review.