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21 results

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Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Among authors: carling pj. Mol Psychiatry. 2024 Feb 15. doi: 10.1038/s41380-024-02463-2. Online ahead of print. Mol Psychiatry. 2024. PMID: 38361127
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.
Lang C, Campbell KR, Ryan BJ, Carling P, Attar M, Vowles J, Perestenko OV, Bowden R, Baig F, Kasten M, Hu MT, Cowley SA, Webber C, Wade-Martins R. Lang C, et al. Cell Stem Cell. 2019 Jan 3;24(1):93-106.e6. doi: 10.1016/j.stem.2018.10.023. Epub 2018 Nov 29. Cell Stem Cell. 2019. PMID: 30503143 Free PMC article.
Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's disease.
Carling PJ, Mortiboys H, Green C, Mihaylov S, Sandor C, Schwartzentruber A, Taylor R, Wei W, Hastings C, Wong S, Lo C, Evetts S, Clemmens H, Wyles M, Willcox S, Payne T, Hughes R, Ferraiuolo L, Webber C, Hide W, Wade-Martins R, Talbot K, Hu MT, Bandmann O. Carling PJ, et al. Prog Neurobiol. 2020 Apr;187:101772. doi: 10.1016/j.pneurobio.2020.101772. Epub 2020 Feb 11. Prog Neurobiol. 2020. PMID: 32058042 Free article.
Mutation-specific effects in germline transmission of pathogenic mtDNA variants.
Otten ABC, Sallevelt SCEH, Carling PJ, Dreesen JCFM, Drüsedau M, Spierts S, Paulussen ADC, de Die-Smulders CEM, Herbert M, Chinnery PF, Samuels DC, Lindsey P, Smeets HJM. Otten ABC, et al. Among authors: carling pj. Hum Reprod. 2018 Jul 1;33(7):1331-1341. doi: 10.1093/humrep/dey114. Hum Reprod. 2018. PMID: 29850888 Free PMC article.
Mitochondrial DNA sequence characteristics modulate the size of the genetic bottleneck.
Wilson IJ, Carling PJ, Alston CL, Floros VI, Pyle A, Hudson G, Sallevelt SC, Lamperti C, Carelli V, Bindoff LA, Samuels DC, Wonnapinij P, Zeviani M, Taylor RW, Smeets HJ, Horvath R, Chinnery PF. Wilson IJ, et al. Among authors: carling pj. Hum Mol Genet. 2016 Mar 1;25(5):1031-41. doi: 10.1093/hmg/ddv626. Epub 2016 Jan 5. Hum Mol Genet. 2016. PMID: 26740552 Free PMC article.
Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome.
Rajan P, Dalgliesh C, Carling PJ, Buist T, Zhang C, Grellscheid SN, Armstrong K, Stockley J, Simillion C, Gaughan L, Kalna G, Zhang MQ, Robson CN, Leung HY, Elliott DJ. Rajan P, et al. Among authors: carling pj. PLoS One. 2011;6(12):e29088. doi: 10.1371/journal.pone.0029088. Epub 2011 Dec 14. PLoS One. 2011. PMID: 22194994 Free PMC article.
21 results