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Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders.
Rao X, Thapa KS, Chen AB, Lin H, Gao H, Reiter JL, Hargreaves KA, Ipe J, Lai D, Xuei X, Wang Y, Gu H, Kapoor M, Farris SP, Tischfield J, Foroud T, Goate AM, Skaar TC, Mayfield RD, Edenberg HJ, Liu Y. Rao X, et al. Among authors: xuei x. Mol Psychiatry. 2021 Apr;26(4):1142-1151. doi: 10.1038/s41380-019-0508-z. Epub 2019 Sep 2. Mol Psychiatry. 2021. PMID: 31477794 Free PMC article.
Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons.
Prytkova I, Liu Y, Fernando M, Gameiro-Ros I, Popova D, Kamarajan C, Xuei X, Chorlian DB, Edenberg HJ, Tischfield JA, Porjesz B, Pang ZP, Hart RP, Goate A, Slesinger PA. Prytkova I, et al. Among authors: xuei x. bioRxiv [Preprint]. 2024 Jan 13:2023.03.22.533236. doi: 10.1101/2023.03.22.533236. bioRxiv. 2024. PMID: 36993693 Free PMC article. Updated. Preprint.
Ethanol activates immune response in lymphoblastoid cells.
McClintick JN, Tischfield JA, Deng L, Kapoor M, Xuei X, Edenberg HJ. McClintick JN, et al. Among authors: xuei x. Alcohol. 2019 Sep;79:81-91. doi: 10.1016/j.alcohol.2019.01.001. Epub 2019 Jan 9. Alcohol. 2019. PMID: 30639126 Free PMC article.
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
Karlsson Linnér R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S; COGA Collaborators; Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM. Karlsson Linnér R, et al. Nat Neurosci. 2021 Oct;24(10):1367-1376. doi: 10.1038/s41593-021-00908-3. Epub 2021 Aug 26. Nat Neurosci. 2021. PMID: 34446935 Free PMC article.
The tachykinin receptor 3 is associated with alcohol and cocaine dependence.
Foroud T, Wetherill LF, Kramer J, Tischfield JA, Nurnberger JI Jr, Schuckit MA, Xuei X, Edenberg HJ. Foroud T, et al. Among authors: xuei x. Alcohol Clin Exp Res. 2008 Jun;32(6):1023-30. doi: 10.1111/j.1530-0277.2008.00663.x. Epub 2008 Apr 15. Alcohol Clin Exp Res. 2008. PMID: 18422838 Free PMC article.
115 results