Bumbak F - Search Results

1

Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.

Russell IC, Zhang X, Bumbak F, McNeill SM, Josephs TM, Leeming MG, Christopoulos G, Venugopal H, Flocco MM, Sexton PM, Wootten D, Belousoff MJ. Russell IC, et al. Among authors: bumbak f. Biochemistry. 2024 Mar 5;63(5):625-631. doi: 10.1021/acs.biochem.3c00647. Epub 2024 Feb 20. Biochemistry. 2024. PMID: 38376112

2

Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314.

Bumbak F, Bower JB, Zemmer SC, Inoue A, Pons M, Paniagua JC, Yan F, Ford J, Wu H, Robson SA, Bathgate RAD, Scott DJ, Gooley PR, Ziarek JJ. Bumbak F, et al. Nat Commun. 2023 Jun 7;14(1):3328. doi: 10.1038/s41467-023-38894-8. Nat Commun. 2023. PMID: 37286565 Free PMC article.

3

Characterisation of a cell-free synthesised G-protein coupled receptor.

Shilling PJ, Bumbak F, Scott DJ, Bathgate RAD, Gooley PR. Shilling PJ, et al. Among authors: bumbak f. Sci Rep. 2017 Apr 24;7(1):1094. doi: 10.1038/s41598-017-01227-z. Sci Rep. 2017. PMID: 28439124 Free PMC article.

4

Conformational Changes in Tyrosine 11 of Neurotensin Are Required to Activate the Neurotensin Receptor 1.

Bumbak F, Thomas T, Noonan-Williams BJ, Vaid TM, Yan F, Whitehead AR, Bruell S, Kocan M, Tan X, Johnson MA, Bathgate RAD, Chalmers DK, Gooley PR, Scott DJ. Bumbak F, et al. ACS Pharmacol Transl Sci. 2020 Apr 29;3(4):690-705. doi: 10.1021/acsptsci.0c00026. eCollection 2020 Aug 14. ACS Pharmacol Transl Sci. 2020. PMID: 32832871 Free PMC article.

5

Optimization and ¹³CH₃ methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies.

Bumbak F, Keen AC, Gunn NJ, Gooley PR, Bathgate RAD, Scott DJ. Bumbak F, et al. Biochim Biophys Acta Biomembr. 2018 Jun;1860(6):1372-1383. doi: 10.1016/j.bbamem.2018.03.020. Epub 2018 Mar 26. Biochim Biophys Acta Biomembr. 2018. PMID: 29596791 Free article.

6

Effect of Ligands and Transducers on the Neurotensin Receptor 1 Conformational Ensemble.

Dixon AD, Inoue A, Robson SA, Culhane KJ, Trinidad JC, Sivaramakrishnan S, Bumbak F, Ziarek JJ. Dixon AD, et al. Among authors: bumbak f. J Am Chem Soc. 2022 Jun 15;144(23):10241-10250. doi: 10.1021/jacs.2c00828. Epub 2022 Jun 1. J Am Chem Soc. 2022. PMID: 35647863 Free PMC article.

7

Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS₁).

Bumbak F, Pons M, Inoue A, Paniagua JC, Yan F, Wu H, Robson SA, Bathgate RAD, Scott DJ, Gooley PR, Ziarek JJ. Bumbak F, et al. Cell Rep. 2023 Jan 31;42(1):112015. doi: 10.1016/j.celrep.2023.112015. Epub 2023 Jan 20. Cell Rep. 2023. PMID: 36680775 Free PMC article.

8

Expression and Purification of a Functional E. coli ¹³CH₃-Methionine-Labeled Thermostable Neurotensin Receptor 1 Variant for Solution NMR Studies.

Bumbak F, Bathgate RAD, Scott DJ, Gooley PR. Bumbak F, et al. Methods Mol Biol. 2019;1947:31-55. doi: 10.1007/978-1-4939-9121-1_3. Methods Mol Biol. 2019. PMID: 30969410

9

Expanding the genotype and phenotype spectrum of SYT1-associated neurodevelopmental disorder.

Melland H, Bumbak F, Kolesnik-Taylor A, Ng-Cordell E, John A, Constantinou P, Joss S, Larsen M, Fagerberg C, Laulund LW, Thies J, Emslie F, Willemsen M, Kleefstra T, Pfundt R, Barrick R, Chang R, Loong L, Alfadhel M, van der Smagt J, Nizon M, Kurian MA, Scott DJ, Ziarek JJ, Gordon SL, Baker K. Melland H, et al. Among authors: bumbak f. Genet Med. 2022 Apr;24(4):880-893. doi: 10.1016/j.gim.2021.12.002. Epub 2022 Jan 29. Genet Med. 2022. PMID: 35101335 Free PMC article.

10

SYT1-associated neurodevelopmental disorder: a case series.

Baker K, Gordon SL, Melland H, Bumbak F, Scott DJ, Jiang TJ, Owen D, Turner BJ, Boyd SG, Rossi M, Al-Raqad M, Elpeleg O, Peck D, Mancini GMS, Wilke M, Zollino M, Marangi G, Weigand H, Borggraefe I, Haack T, Stark Z, Sadedin S; Broad Center for Mendelian Genomics; Tan TY, Jiang Y, Gibbs RA, Ellingwood S, Amaral M, Kelley W, Kurian MA, Cousin MA, Raymond FL. Baker K, et al. Among authors: bumbak f. Brain. 2018 Sep 1;141(9):2576-2591. doi: 10.1093/brain/awy209. Brain. 2018. PMID: 30107533 Free PMC article.

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