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Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.
Russell IC, Zhang X, Bumbak F, McNeill SM, Josephs TM, Leeming MG, Christopoulos G, Venugopal H, Flocco MM, Sexton PM, Wootten D, Belousoff MJ. Russell IC, et al. Among authors: leeming mg. Biochemistry. 2024 Mar 5;63(5):625-631. doi: 10.1021/acs.biochem.3c00647. Epub 2024 Feb 20. Biochemistry. 2024. PMID: 38376112
Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868.
Taki AC, Wang T, Nguyen NN, Ang CS, Leeming MG, Nie S, Byrne JJ, Young ND, Zheng Y, Ma G, Korhonen PK, Koehler AV, Williamson NA, Hofmann A, Chang BCH, Häberli C, Keiser J, Jabbar A, Sleebs BE, Gasser RB. Taki AC, et al. Among authors: leeming mg. Front Pharmacol. 2022 Oct 14;13:1014804. doi: 10.3389/fphar.2022.1014804. eCollection 2022. Front Pharmacol. 2022. PMID: 36313370 Free PMC article.
The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis.
Maunders EA, Ngu DHY, Ganio K, Hossain SI, Lim BYJ, Leeming MG, Luo Z, Tan A, Deplazes E, Kobe B, McDevitt CA. Maunders EA, et al. Among authors: leeming mg. Front Microbiol. 2022 May 24;13:903146. doi: 10.3389/fmicb.2022.903146. eCollection 2022. Front Microbiol. 2022. PMID: 35685933 Free PMC article.
Comparative structure activity and target exploration of 1,2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans.
Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Williamson N, Chang BCH, Jabbar A, Sleebs BE, Gasser RB. Shanley HT, et al. Among authors: leeming mg. Int J Parasitol Drugs Drug Resist. 2024 Mar 19;25:100534. doi: 10.1016/j.ijpddr.2024.100534. Online ahead of print. Int J Parasitol Drugs Drug Resist. 2024. PMID: 38554597 Free PMC article.
Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans.
Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Nie S, Williamson N, Zheng Y, Young ND, Korhonen PK, Hofmann A, Wells TNC, Jabbar A, Sleebs BE, Gasser RB. Shanley HT, et al. Among authors: leeming mg. Bioorg Med Chem. 2024 Jan 15;98:117540. doi: 10.1016/j.bmc.2023.117540. Epub 2023 Dec 3. Bioorg Med Chem. 2024. PMID: 38134663 Free article.
28 results