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497 results

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Page 1
Targeting nuclear receptor corepressors for reversible male contraception.
Hong SH, Castro G, Wang D, Nofsinger R, Kane M, Folias A, Atkins AR, Yu RT, Napoli JL, Sassone-Corsi P, de Rooij DG, Liddle C, Downes M, Evans RM. Hong SH, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2320129121. doi: 10.1073/pnas.2320129121. Epub 2024 Feb 20. Proc Natl Acad Sci U S A. 2024. PMID: 38377195
Unique forms of human and mouse nuclear receptor corepressor SMRT.
Ordentlich P, Downes M, Xie W, Genin A, Spinner NB, Evans RM. Ordentlich P, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2639-44. doi: 10.1073/pnas.96.6.2639. Proc Natl Acad Sci U S A. 1999. PMID: 10077563 Free PMC article.
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis.
Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, Lee CH, Evans RM. Nofsinger RR, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):20021-6. doi: 10.1073/pnas.0811012105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066220 Free PMC article.
Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.
Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Hong SH, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10381-10386. doi: 10.1073/pnas.1809480115. Epub 2018 Sep 25. Proc Natl Acad Sci U S A. 2018. PMID: 30254164 Free PMC article.
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease.
Chang C, Loo CS, Zhao X, Solt LA, Liang Y, Bapat SP, Cho H, Kamenecka TM, Leblanc M, Atkins AR, Yu RT, Downes M, Burris TP, Evans RM, Zheng Y. Chang C, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18528-18536. doi: 10.1073/pnas.1907563116. Epub 2019 Aug 27. Proc Natl Acad Sci U S A. 2019. PMID: 31455731 Free PMC article.
Identification of a nuclear domain with deacetylase activity.
Downes M, Ordentlich P, Kao HY, Alvarez JG, Evans RM. Downes M, et al. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10330-5. doi: 10.1073/pnas.97.19.10330. Proc Natl Acad Sci U S A. 2000. PMID: 10984530 Free PMC article.
Corepressors and nuclear hormone receptor function.
Ordentlich P, Downes M, Evans RM. Ordentlich P, et al. Among authors: downes m. Curr Top Microbiol Immunol. 2001;254:101-16. doi: 10.1007/978-3-662-10595-5_5. Curr Top Microbiol Immunol. 2001. PMID: 11190569 Review. No abstract available.
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Sonoda J, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2198-203. doi: 10.1073/pnas.0409481102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671183 Free PMC article.
497 results