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Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.
Kim IK, Diamond MS, Yuan S, Kemp SB, Kahn BM, Li Q, Lin JH, Li J, Norgard RJ, Thomas SK, Merolle M, Katsuda T, Tobias JW, Baslan T, Politi K, Vonderheide RH, Stanger BZ. Kim IK, et al. Among authors: merolle m. Nat Commun. 2024 Feb 20;15(1):1532. doi: 10.1038/s41467-024-46048-7. Nat Commun. 2024. PMID: 38378697 Free PMC article.
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy.
Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ. Metzloff AE, et al. Among authors: merolle m. Adv Mater. 2024 Feb 28:e2313226. doi: 10.1002/adma.202313226. Online ahead of print. Adv Mater. 2024. PMID: 38419362
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery.
Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ. Patel SK, et al. Among authors: merolle m. Theranostics. 2024 Jan 1;14(1):1-16. doi: 10.7150/thno.89913. eCollection 2024. Theranostics. 2024. PMID: 38164140 Free PMC article.
Absence of ATM leads to altered NK cell function in mice.
Covino DA, Desimio MG, Giovinazzo A, de Oliveira BSP, Merolle M, Marazziti D, Pellegrini M, Doria M. Covino DA, et al. Among authors: merolle m. Clin Immunol. 2024 Jun;263:110233. doi: 10.1016/j.clim.2024.110233. Epub 2024 Apr 30. Clin Immunol. 2024. PMID: 38697554
Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses.
Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, Christian DA, Striepen B, Hunter CA. Haskins BE, et al. Among authors: merolle mi. Mucosal Immunol. 2024 Mar 18:S1933-0219(24)00022-9. doi: 10.1016/j.mucimm.2024.03.003. Online ahead of print. Mucosal Immunol. 2024. PMID: 38508522 Free article.
Dendritic cell-mediated responses to secreted Cryptosporidium effectors are required for parasite-specific CD8 + T cell responses.
Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, Christian DA, Striepen B, Hunter CA. Haskins BE, et al. Among authors: merolle mi. bioRxiv [Preprint]. 2023 Aug 18:2023.08.16.553566. doi: 10.1101/2023.08.16.553566. bioRxiv. 2023. PMID: 37645924 Free PMC article. Updated. Preprint.
ATM Kinase Dead: From Ataxia Telangiectasia Syndrome to Cancer.
Putti S, Giovinazzo A, Merolle M, Falchetti ML, Pellegrini M. Putti S, et al. Among authors: merolle m. Cancers (Basel). 2021 Nov 1;13(21):5498. doi: 10.3390/cancers13215498. Cancers (Basel). 2021. PMID: 34771661 Free PMC article. Review.
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