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Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.
Kim IK, Diamond MS, Yuan S, Kemp SB, Kahn BM, Li Q, Lin JH, Li J, Norgard RJ, Thomas SK, Merolle M, Katsuda T, Tobias JW, Baslan T, Politi K, Vonderheide RH, Stanger BZ. Kim IK, et al. Among authors: vonderheide rh. Nat Commun. 2024 Feb 20;15(1):1532. doi: 10.1038/s41467-024-46048-7. Nat Commun. 2024. PMID: 38378697 Free PMC article.
EMT and dissemination precede pancreatic tumor formation.
Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ. Rhim AD, et al. Among authors: vonderheide rh. Cell. 2012 Jan 20;148(1-2):349-61. doi: 10.1016/j.cell.2011.11.025. Cell. 2012. PMID: 22265420 Free PMC article.
CD40 immunotherapy for pancreatic cancer.
Vonderheide RH, Bajor DL, Winograd R, Evans RA, Bayne LJ, Beatty GL. Vonderheide RH, et al. Cancer Immunol Immunother. 2013 May;62(5):949-54. doi: 10.1007/s00262-013-1427-5. Epub 2013 Apr 16. Cancer Immunol Immunother. 2013. PMID: 23589109 Free PMC article. Review.
Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma.
Winograd R, Byrne KT, Evans RA, Odorizzi PM, Meyer AR, Bajor DL, Clendenin C, Stanger BZ, Furth EE, Wherry EJ, Vonderheide RH. Winograd R, et al. Among authors: vonderheide rh. Cancer Immunol Res. 2015 Apr;3(4):399-411. doi: 10.1158/2326-6066.CIR-14-0215. Epub 2015 Feb 12. Cancer Immunol Res. 2015. PMID: 25678581 Free PMC article.
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen.
Evans RA, Diamond MS, Rech AJ, Chao T, Richardson MW, Lin JH, Bajor DL, Byrne KT, Stanger BZ, Riley JL, Markosyan N, Winograd R, Vonderheide RH. Evans RA, et al. Among authors: vonderheide rh. JCI Insight. 2016 Sep 8;1(14):e88328. doi: 10.1172/jci.insight.88328. JCI Insight. 2016. PMID: 27642636 Free PMC article.
207 results