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Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy.
Hoogenboezem EN, Patel SS, Lo JH, Cavnar AB, Babb LM, Francini N, Gbur EF, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL. Hoogenboezem EN, et al. Among authors: allen rm. Nat Commun. 2024 Feb 21;15(1):1581. doi: 10.1038/s41467-024-45609-0. Nat Commun. 2024. PMID: 38383524 Free PMC article.
LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8.
Allen RM, Michell DL, Cavnar AB, Zhu W, Makhijani N, Contreras DM, Raby CA, Semler EM, DeJulius C, Castleberry M, Zhang Y, Ramirez-Solano M, Zhao S, Duvall C, Doran AC, Sheng Q, Linton MF, Vickers KC. Allen RM, et al. Nat Cell Biol. 2022 Dec;24(12):1701-1713. doi: 10.1038/s41556-022-01030-7. Epub 2022 Dec 6. Nat Cell Biol. 2022. PMID: 36474072 Free PMC article.
Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions.
Michell DL, Allen RM, Cavnar AB, Contreras DM, Yu M, Semler EM, Massick C, Raby CA, Castleberry M, Ramirez MA, Zhu W, May-Zhang L, Ifrim A, Carr JJ, Terry JG, Schwendeman A, Davies SS, Sheng Q, Linton MF, Vickers KC. Michell DL, et al. Among authors: allen rm. J Biol Chem. 2022 Jun;298(6):101952. doi: 10.1016/j.jbc.2022.101952. Epub 2022 Apr 18. J Biol Chem. 2022. PMID: 35447119 Free PMC article.
Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins.
Allen RM, Zhao S, Ramirez Solano MA, Zhu W, Michell DL, Wang Y, Shyr Y, Sethupathy P, Linton MF, Graf GA, Sheng Q, Vickers KC. Allen RM, et al. J Extracell Vesicles. 2018 Aug 13;7(1):1506198. doi: 10.1080/20013078.2018.1506198. eCollection 2018. J Extracell Vesicles. 2018. PMID: 30128086 Free PMC article.
Profile of Podocyte Translatome During Development of Type 2 and Type 1 Diabetic Nephropathy Using Podocyte-Specific TRAP mRNA RNA-seq.
Wang Y, Niu A, Pan Y, Cao S, Terker AS, Wang S, Fan X, Toth CL, Ramirez Solano MA, Michell DL, Contreras D, Allen RM, Zhu W, Sheng Q, Fogo AB, Vickers KC, Zhang MZ, Harris RC. Wang Y, et al. Among authors: allen rm. Diabetes. 2021 Oct;70(10):2377-2390. doi: 10.2337/db21-0110. Epub 2021 Jul 7. Diabetes. 2021. PMID: 34233930 Free PMC article.
Dysfunctional high-density lipoproteins in children with chronic kidney disease.
Kaseda R, Jabs K, Hunley TE, Jones D, Bian A, Allen RM, Vickers KC, Yancey PG, Linton MF, Fazio S, Kon V. Kaseda R, et al. Among authors: allen rm. Metabolism. 2015 Feb;64(2):263-73. doi: 10.1016/j.metabol.2014.10.020. Epub 2014 Oct 25. Metabolism. 2015. PMID: 25467845 Free PMC article.
225 results