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B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. Afzali AM, et al. Among authors: lammens k. Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8. Epub 2024 Feb 21. Nature. 2024. PMID: 38383779 Free PMC article.
Deletional tolerance prevents AQP4-directed autoimmunity in mice.
Vogel AL, Knier B, Lammens K, Kalluri SR, Kuhlmann T, Bennett JL, Korn T. Vogel AL, et al. Among authors: lammens k. Eur J Immunol. 2017 Mar;47(3):458-469. doi: 10.1002/eji.201646855. Epub 2017 Jan 25. Eur J Immunol. 2017. PMID: 28058717 Free PMC article.
Molecular basis of human ATM kinase inhibition.
Stakyte K, Rotheneder M, Lammens K, Bartho JD, Grädler U, Fuchß T, Pehl U, Alt A, van de Logt E, Hopfner KP. Stakyte K, et al. Among authors: lammens k. Nat Struct Mol Biol. 2021 Oct;28(10):789-798. doi: 10.1038/s41594-021-00654-x. Epub 2021 Sep 23. Nat Struct Mol Biol. 2021. PMID: 34556870
Mechanistic understanding of human SLFN11.
Metzner FJ, Wenzl SJ, Kugler M, Krebs S, Hopfner KP, Lammens K. Metzner FJ, et al. Among authors: lammens k. Nat Commun. 2022 Sep 17;13(1):5464. doi: 10.1038/s41467-022-33123-0. Nat Commun. 2022. PMID: 36115853 Free PMC article.
Molecular architecture and regulation of BCL10-MALT1 filaments.
Schlauderer F, Seeholzer T, Desfosses A, Gehring T, Strauss M, Hopfner KP, Gutsche I, Krappmann D, Lammens K. Schlauderer F, et al. Among authors: lammens k. Nat Commun. 2018 Oct 2;9(1):4041. doi: 10.1038/s41467-018-06573-8. Nat Commun. 2018. PMID: 30279415 Free PMC article.
Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation.
Bérouti M, Lammens K, Heiss M, Hansbauer L, Bauernfried S, Stöckl J, Pinci F, Piseddu I, Greulich W, Wang M, Jung C, Fröhlich T, Carell T, Hopfner KP, Hornung V. Bérouti M, et al. Among authors: lammens k. Immunity. 2024 Apr 26:S1074-7613(24)00215-2. doi: 10.1016/j.immuni.2024.04.010. Online ahead of print. Immunity. 2024. PMID: 38697119 Free article.
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.
Pippig DA, Hellmuth JC, Cui S, Kirchhofer A, Lammens K, Lammens A, Schmidt A, Rothenfusser S, Hopfner KP. Pippig DA, et al. Among authors: lammens k, lammens a. Nucleic Acids Res. 2009 Apr;37(6):2014-25. doi: 10.1093/nar/gkp059. Epub 2009 Feb 10. Nucleic Acids Res. 2009. PMID: 19208642 Free PMC article.
39 results