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Tumor Fraction Correlates With Detection of Actionable Variants Across > 23,000 Circulating Tumor DNA Samples.
Husain H, Pavlick DC, Fendler BJ, Madison RW, Decker B, Gjoerup O, Parachoniak CA, McLaughlin-Drubin M, Erlich RL, Schrock AB, Frampton GM, Das Thakur M, Oxnard GR, Tukachinsky H. Husain H, et al. Among authors: tukachinsky h. JCO Precis Oncol. 2022 Oct;6:e2200261. doi: 10.1200/PO.22.00261. JCO Precis Oncol. 2022. PMID: 36265119 Free PMC article.
Unique Spectrum of Activating BRAF Alterations in Prostate Cancer.
Chehrazi-Raffle A, Tukachinsky H, Toye E, Sivakumar S, Schrock AB, Bergom HE, Ebrahimi H, Pal S, Dorff T, Agarwal N, Mahal BA, Oxnard GR, Hwang J, Antonarakis ES. Chehrazi-Raffle A, et al. Among authors: tukachinsky h. Clin Cancer Res. 2023 Oct 2;29(19):3948-3957. doi: 10.1158/1078-0432.CCR-23-1393. Clin Cancer Res. 2023. PMID: 37477913 Free PMC article.
SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis-Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer.
Swami U, Graf RP, Nussenzveig RH, Fisher V, Tukachinsky H, Schrock AB, Li G, Ross JS, Sayegh N, Tripathi N, Mathew Thomas V, Oxnard GR, Antonarakis ES, Agarwal N. Swami U, et al. Among authors: tukachinsky h. Clin Cancer Res. 2022 Nov 14;28(22):4917-4925. doi: 10.1158/1078-0432.CCR-22-2228. Clin Cancer Res. 2022. PMID: 36088616
Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types.
Kasi PM, Lee JK, Pasquina LW, Decker B, Vanden Borre P, Pavlick DC, Allen JM, Parachoniak C, Quintanilha JCF, Graf RP, Schrock AB, Oxnard GR, Lovly CM, Tukachinsky H, Subbiah V. Kasi PM, et al. Among authors: tukachinsky h. Clin Cancer Res. 2024 Feb 16;30(4):836-848. doi: 10.1158/1078-0432.CCR-23-2693. Clin Cancer Res. 2024. PMID: 38060240 Free PMC article.
Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma.
Margolis M, Janovitz T, Laird J, Mata DA, Montesion M, Lee JK, Madison RW, Schrock AB, Tukachinsky H, Allen JM, Erlich R, Hiemenz MC, Huang RSP, Elvin J, Vergilio JA, Lin DI, Ross J, Oxnard G, Decker B. Margolis M, et al. Among authors: tukachinsky h. Mod Pathol. 2022 Nov;35(11):1618-1623. doi: 10.1038/s41379-022-01126-3. Epub 2022 Aug 15. Mod Pathol. 2022. PMID: 35970994 Free article.
Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer.
Necchi A, Cucchiara V, Grivas P, Bratslavsky G, Jacob J, Spiess PE, Sokol ES, Killian JK, Lin D, Ramkissoon S, Huang RSP, Madison RW, Venstrom JM, Schrock AB, Danziger N, Decker B, Gjoerup O, Graf RP, Oxnard GR, Tukachinsky H, Ross JS. Necchi A, et al. Among authors: tukachinsky h. Cancer. 2021 Dec 15;127(24):4557-4564. doi: 10.1002/cncr.33865. Epub 2021 Aug 11. Cancer. 2021. PMID: 34379803 Free article.
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.
Sivakumar S, Jin DX, Tukachinsky H, Murugesan K, McGregor K, Danziger N, Pavlick D, Gjoerup O, Ross JS, Harmon R, Chung J, Decker B, Dennis L, Frampton GM, Molinero L, Oesterreich S, Venstrom JM, Oxnard GR, Hegde PS, Sokol ES. Sivakumar S, et al. Among authors: tukachinsky h. Nat Commun. 2022 Dec 5;13(1):7495. doi: 10.1038/s41467-022-35245-x. Nat Commun. 2022. PMID: 36470901 Free PMC article.
28 results