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Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolism.
Varghese S, Srivastava A, Wong SW, Le T, Pitcher N, Mesnard M, Lallemand C, Rahmani R, Moawad SR, Huang F, He T, Sleebs BE, Barrett MP, Sykes ML, Avery VM, Creek DJ, Baell JB. Varghese S, et al. Among authors: srivastava a. Eur J Med Chem. 2024 Mar 15;268:116162. doi: 10.1016/j.ejmech.2024.116162. Epub 2024 Jan 17. Eur J Med Chem. 2024. PMID: 38394930 Free article.
Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity.
Cao E, Watt MJ, Nowell CJ, Quach T, Simpson JS, De Melo Ferreira V, Agarwal S, Chu H, Srivastava A, Anderson D, Gracia G, Lam A, Segal G, Hong J, Hu L, Phang KL, Escott ABJ, Windsor JA, Phillips ARJ, Creek DJ, Harvey NL, Porter CJH, Trevaskis NL. Cao E, et al. Among authors: srivastava a. Nat Metab. 2021 Sep;3(9):1175-1188. doi: 10.1038/s42255-021-00457-w. Epub 2021 Sep 20. Nat Metab. 2021. PMID: 34545251
7,034 results