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Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling.
bioRxiv [Preprint]. 2024 Feb 15:2024.02.14.580335. doi: 10.1101/2024.02.14.580335.
bioRxiv. 2024.
PMID: 38405895
Free PMC article.
Preprint.
Spatiotemporal Optical Control of Gαq-PLCβ Interactions.
Ubeysinghe S, Kankanamge D, Thotamune W, Wijayaratna D, Mohan TM 3rd, Karunarathne A.
Ubeysinghe S, et al.
ACS Synth Biol. 2024 Jan 19;13(1):242-258. doi: 10.1021/acssynbio.3c00490. Epub 2023 Dec 13.
ACS Synth Biol. 2024.
PMID: 38092428
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Spatiotemporal optical control of Gαq-PLCβ interactions.
Ubeysinghe S, Kankanamge D, Thotamune W, Wijayaratna D, Mohan TM, Karunarathne A.
Ubeysinghe S, et al.
bioRxiv [Preprint]. 2023 Aug 11:2023.08.10.552801. doi: 10.1101/2023.08.10.552801.
bioRxiv. 2023.
PMID: 37609229
Free PMC article.
Updated.
Preprint.
Item in Clipboard
Molecular regulation of PLCβ signaling.
Ubeysinghe S, Wijayaratna D, Kankanamge D, Karunarathne A.
Ubeysinghe S, et al.
Methods Enzymol. 2023;682:17-52. doi: 10.1016/bs.mie.2023.01.001. Epub 2023 Feb 22.
Methods Enzymol. 2023.
PMID: 36948701
Review.
Item in Clipboard
The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics.
Wijayaratna D, Ratnayake K, Ubeysinghe S, Kankanamge D, Tennakoon M, Karunarathne A.
Wijayaratna D, et al. Among authors: ubeysinghe s.
Sci Rep. 2023 Feb 16;13(1):2771. doi: 10.1038/s41598-023-29639-0.
Sci Rep. 2023.
PMID: 36797332
Free PMC article.
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Dissociation of the G protein βγ from the Gq-PLCβ complex partially attenuates PIP2 hydrolysis.
Kankanamge D, Ubeysinghe S, Tennakoon M, Pantula PD, Mitra K, Giri L, Karunarathne A.
Kankanamge D, et al. Among authors: ubeysinghe s.
J Biol Chem. 2021 Jan-Jun;296:100702. doi: 10.1016/j.jbc.2021.100702. Epub 2021 Apr 24.
J Biol Chem. 2021.
PMID: 33901492
Free PMC article.
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Subtype-dependent regulation of Gβγ signalling.
Tennakoon M, Senarath K, Kankanamge D, Ratnayake K, Wijayaratna D, Olupothage K, Ubeysinghe S, Martins-Cannavino K, Hébert TE, Karunarathne A.
Tennakoon M, et al. Among authors: ubeysinghe s.
Cell Signal. 2021 Jun;82:109947. doi: 10.1016/j.cellsig.2021.109947. Epub 2021 Feb 11.
Cell Signal. 2021.
PMID: 33582184
Free PMC article.
Review.
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