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Type 1 interferons and Foxo1 down-regulation play a key role in age-related T-cell exhaustion in mice.
Durand A, Bonilla N, Level T, Ginestet Z, Lombès A, Guichard V, Germain M, Jacques S, Letourneur F, Do Cruzeiro M, Marchiol C, Renault G, Le Gall M, Charvet C, Le Bon A, Martin B, Auffray C, Lucas B. Durand A, et al. Among authors: letourneur f. Nat Commun. 2024 Feb 26;15(1):1718. doi: 10.1038/s41467-024-45984-8. Nat Commun. 2024. PMID: 38409097 Free PMC article.
Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth.
Lévy J, Cacheux W, Bara MA, L'Hermitte A, Lepage P, Fraudeau M, Trentesaux C, Lemarchand J, Durand A, Crain AM, Marchiol C, Renault G, Dumont F, Letourneur F, Delacre M, Schmitt A, Terris B, Perret C, Chamaillard M, Couty JP, Romagnolo B. Lévy J, et al. Among authors: letourneur f. Nat Cell Biol. 2015 Aug;17(8):1062-73. doi: 10.1038/ncb3206. Epub 2015 Jul 27. Nat Cell Biol. 2015. PMID: 26214133
Axin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect.
Sanson R, Lazzara SL, Cune D, Pitasi CL, Trentesaux C, Fraudeau M, Letourneur F, Saintpierre B, Le Gall M, Bossard P, Terris B, Finetti P, Bertucci F, Mamessier E, Romagnolo B, Perret C. Sanson R, et al. Among authors: letourneur f. Cell Mol Gastroenterol Hepatol. 2023;15(3):689-715. doi: 10.1016/j.jcmgh.2022.10.017. Epub 2022 Nov 8. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36356835 Free PMC article.
Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity.
Trentesaux C, Fraudeau M, Pitasi CL, Lemarchand J, Jacques S, Duche A, Letourneur F, Naser E, Bailly K, Schmitt A, Perret C, Romagnolo B. Trentesaux C, et al. Among authors: letourneur f. Proc Natl Acad Sci U S A. 2020 May 19;117(20):11136-11146. doi: 10.1073/pnas.1917174117. Epub 2020 May 5. Proc Natl Acad Sci U S A. 2020. PMID: 32371487 Free PMC article.
Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.
Ambolet-Camoit A, Ottolenghi C, Leblanc A, Kim MJ, Letourneur F, Jacques S, Cagnard N, Guguen-Guillouzo C, Barouki R, Aggerbeck M. Ambolet-Camoit A, et al. Among authors: letourneur f. Biochimie. 2015 Sep;116:79-91. doi: 10.1016/j.biochi.2015.07.003. Epub 2015 Jul 6. Biochimie. 2015. PMID: 26159488 Free article.
192 results