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The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
Nat Immunol. 2024 Mar;25(3):432-447. doi: 10.1038/s41590-024-01756-6. Epub 2024 Feb 26.
Nat Immunol. 2024.
PMID: 38409259
Free PMC article.
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Linnerbauer M, Beyer T, Nirschl L, Farrenkopf D, Lößlein L, Vandrey O, Peter A, Tsaktanis T, Kebir H, Laplaud D, Oellinger R, Engleitner T, Alvarez JI, Rad R, Korn T, Hemmer B, Quintana FJ, Rothhammer V.
Linnerbauer M, et al. Among authors: vandrey o.
Nat Commun. 2023 Sep 9;14(1):5555. doi: 10.1038/s41467-023-40982-8.
Nat Commun. 2023.
PMID: 37689786
Free PMC article.
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Regulation of the programmed cell death protein 1/programmed cell death ligand 1 axis in relapsing-remitting multiple sclerosis.
Tsaktanis T, Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Peter A, Cirac A, Beyer T, Nirschl L, Grummel V, Mühlau M, Bussas M, Hemmer B, Quintana FJ, Rothhammer V.
Tsaktanis T, et al. Among authors: vandrey o.
Brain Commun. 2023 Jul 25;5(4):fcad206. doi: 10.1093/braincomms/fcad206. eCollection 2023.
Brain Commun. 2023.
PMID: 37564830
Free PMC article.
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Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.
Linnerbauer M, Lößlein L, Vandrey O, Tsaktanis T, Beer A, Naumann UJ, Panier F, Beyer T, Nirschl L, Kuramatsu JB, Winkler J, Quintana FJ, Rothhammer V.
Linnerbauer M, et al. Among authors: vandrey o.
JCI Insight. 2022 Apr 8;7(7):e154824. doi: 10.1172/jci.insight.154824.
JCI Insight. 2022.
PMID: 35393953
Free PMC article.
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Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.
Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Tsaktanis T, Naumann U, Rothhammer V.
Linnerbauer M, et al. Among authors: vandrey o.
Front Immunol. 2022 Jan 3;12:800128. doi: 10.3389/fimmu.2021.800128. eCollection 2021.
Front Immunol. 2022.
PMID: 35046956
Free PMC article.
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