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Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression.
Amin R, Ha NH, Qiu T, Holewinski R, Lam KC, Lopès A, Liu H, Tran AD, Lee MP, Gamage ST, Andresson T, Goldszmid RS, Meier JL, Hunter KW. Amin R, et al. Among authors: hunter kw. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577116. doi: 10.1101/2024.01.24.577116. bioRxiv. 2024. PMID: 38410432 Free PMC article. Preprint.
Genetic insights into the morass of metastatic heterogeneity.
Hunter KW, Amin R, Deasy S, Ha NH, Wakefield L. Hunter KW, et al. Nat Rev Cancer. 2018 Apr;18(4):211-223. doi: 10.1038/nrc.2017.126. Epub 2018 Feb 9. Nat Rev Cancer. 2018. PMID: 29422598 Free PMC article. Review.
Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response.
Amin R, Shukla A, Zhu JJ, Kim S, Wang P, Tian SZ, Tran AD, Paul D, Cappell SD, Burkett S, Liu H, Lee MP, Kruhlak MJ, Dwyer JE, Simpson RM, Hager GL, Ruan Y, Hunter KW. Amin R, et al. Among authors: hunter kw. Nat Commun. 2021 Dec 13;12(1):7216. doi: 10.1038/s41467-021-27451-w. Nat Commun. 2021. PMID: 34903738 Free PMC article.
SMARCD1 is a "Goldilocks" metastasis modifier.
Ross C, Gong LY, Jenkins LM, Ha NH, Majocha M, Hunter K. Ross C, et al. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577061. doi: 10.1101/2024.01.24.577061. bioRxiv. 2024. PMID: 38410477 Free PMC article. Preprint.
Bromodomain 4 activation predicts breast cancer survival.
Crawford NP, Alsarraj J, Lukes L, Walker RC, Officewala JS, Yang HH, Lee MP, Ozato K, Hunter KW. Crawford NP, et al. Among authors: hunter kw. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6380-5. doi: 10.1073/pnas.0710331105. Epub 2008 Apr 21. Proc Natl Acad Sci U S A. 2008. PMID: 18427120 Free PMC article.
164 results