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Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection.
McManus DT, Valanparambil RM, Medina CB, Hu Y, Scharer CD, Sobierajska E, Chang DY, Wieland A, Lee J, Nasti TH, Hashimoto M, Ross JL, Prokhnevska N, Cardenas MA, Gill AL, Clark EC, Abadie K, Kueh HY, Kaye J, Au-Yeung BB, Kissick HT, Ahmed R. McManus DT, et al. Among authors: medina cb. Res Sq [Preprint]. 2024 Feb 12:rs.3.rs-3922168. doi: 10.21203/rs.3.rs-3922168/v1. Res Sq. 2024. PMID: 38410458 Free PMC article. Preprint.
Pannexin 1 drives efficient epithelial repair after tissue injury.
Lucas CD, Medina CB, Bruton FA, Dorward DA, Raymond MH, Tufan T, Etchegaray JI, Barron B, Oremek MEM, Arandjelovic S, Farber E, Onngut-Gumuscu S, Ke E, Whyte MKB, Rossi AG, Ravichandran KS. Lucas CD, et al. Among authors: medina cb. Sci Immunol. 2022 May 13;7(71):eabm4032. doi: 10.1126/sciimmunol.abm4032. Epub 2022 May 13. Sci Immunol. 2022. PMID: 35559667 Free PMC article.
Microbes exploit death-induced nutrient release by gut epithelial cells.
Anderson CJ, Medina CB, Barron BJ, Karvelyte L, Aaes TL, Lambertz I, Perry JSA, Mehrotra P, Gonçalves A, Lemeire K, Blancke G, Andries V, Ghazavi F, Martens A, van Loo G, Vereecke L, Vandenabeele P, Ravichandran KS. Anderson CJ, et al. Among authors: medina cb. Nature. 2021 Aug;596(7871):262-267. doi: 10.1038/s41586-021-03785-9. Epub 2021 Aug 4. Nature. 2021. PMID: 34349263
Deacetylation as a receptor-regulated direct activation switch for pannexin channels.
Chiu YH, Medina CB, Doyle CA, Zhou M, Narahari AK, Sandilos JK, Gonye EC, Gao HY, Guo SY, Parlak M, Lorenz UM, Conrads TP, Desai BN, Ravichandran KS, Bayliss DA. Chiu YH, et al. Among authors: medina cb. Nat Commun. 2021 Jul 23;12(1):4482. doi: 10.1038/s41467-021-24825-y. Nat Commun. 2021. PMID: 34301959 Free PMC article.
ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels.
Narahari AK, Kreutzberger AJ, Gaete PS, Chiu YH, Leonhardt SA, Medina CB, Jin X, Oleniacz PW, Kiessling V, Barrett PQ, Ravichandran KS, Yeager M, Contreras JE, Tamm LK, Bayliss DA. Narahari AK, et al. Among authors: medina cb. Elife. 2021 Jan 7;10:e64787. doi: 10.7554/eLife.64787. Elife. 2021. PMID: 33410749 Free PMC article.
18 results