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Page 1
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.
Dong H, He X, Zhang L, Chen W, Lin YC, Liu SB, Wang H, Nguyen LXT, Li M, Zhu Y, Zhao D, Ghoda L, Serody J, Vincent B, Luznik L, Gojo I, Zeidner J, Su R, Chen J, Sharma R, Pirrotte P, Wu X, Hu W, Han W, Shen B, Kuo YH, Jin J, Salhotra A, Wang J, Marcucci G, Luo YL, Li L. Dong H, et al. Among authors: nguyen lxt. Nat Cancer. 2024 Apr;5(4):601-624. doi: 10.1038/s43018-024-00736-x. Epub 2024 Feb 27. Nat Cancer. 2024. PMID: 38413714 Free PMC article.
Integrative genomics identifies LMO1 as a neuroblastoma oncogene.
Wang K, Diskin SJ, Zhang H, Attiyeh EF, Winter C, Hou C, Schnepp RW, Diamond M, Bosse K, Mayes PA, Glessner J, Kim C, Frackelton E, Garris M, Wang Q, Glaberson W, Chiavacci R, Nguyen L, Jagannathan J, Saeki N, Sasaki H, Grant SF, Iolascon A, Mosse YP, Cole KA, Li H, Devoto M, McGrady PW, London WB, Capasso M, Rahman N, Hakonarson H, Maris JM. Wang K, et al. Nature. 2011 Jan 13;469(7329):216-20. doi: 10.1038/nature09609. Epub 2010 Dec 1. Nature. 2011. PMID: 21124317 Free PMC article.
The unexpected surface of asteroid (101955) Bennu.
Lauretta DS, DellaGiustina DN, Bennett CA, Golish DR, Becker KJ, Balram-Knutson SS, Barnouin OS, Becker TL, Bottke WF, Boynton WV, Campins H, Clark BE, Connolly HC Jr, Drouet d'Aubigny CY, Dworkin JP, Emery JP, Enos HL, Hamilton VE, Hergenrother CW, Howell ES, Izawa MRM, Kaplan HH, Nolan MC, Rizk B, Roper HL, Scheeres DJ, Smith PH, Walsh KJ, Wolner CWV; OSIRIS-REx Team. Lauretta DS, et al. Nature. 2019 Apr;568(7750):55-60. doi: 10.1038/s41586-019-1033-6. Epub 2019 Mar 19. Nature. 2019. PMID: 30890786 Free PMC article.
Shape of (101955) Bennu indicative of a rubble pile with internal stiffness.
Barnouin OS, Daly MG, Palmer EE, Gaskell RW, Weirich JR, Johnson CL, Asad MMA, Roberts JH, Perry ME, Susorney HCM, Daly RT, Bierhaus EB, Seabrook JA, Espiritu RC, Nair AH, Nguyen L, Neumann GA, Ernst CM, Boynton WV, Nolan MC, Adam CD, Moreau MC, Risk B, D'Aubigny CD, Jawin ER, Walsh KJ, Michel P, Schwartz SR, Ballouz RL, Mazarico EM, Scheeres DJ, McMahon J, Bottke W, Sugita S, Hirata N, Hirata N, Watanabe S, Burke KN, DellaGuistina DN, Bennett CA, Lauretta DS; OSIRIS-REx Team.. Barnouin OS, et al. Nat Geosci. 2019 Apr;12(4):247-252. doi: 10.1038/s41561-019-0330-x. Epub 2019 Mar 19. Nat Geosci. 2019. PMID: 31080497 Free PMC article.
OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia.
Kang H, Hoang DH, Valerio M, Pathak K, Zhang L, Buettner R, Chen F, Estrella K, Graff W, Li Z, Xie J, Horne D, Kuo YH, Zhang B, Pirrotte P, Nguyen LXT, Marcucci G. Kang H, et al. Among authors: nguyen lxt. Leukemia. 2024 Mar;38(3):657-662. doi: 10.1038/s41375-024-02146-5. Epub 2024 Jan 17. Leukemia. 2024. PMID: 38233463 Free PMC article. No abstract available.
Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis.
Zhang B, Zhao D, Chen F, Frankhouser D, Wang H, Pathak KV, Dong L, Torres A, Garcia-Mansfield K, Zhang Y, Hoang DH, Chen MH, Tao S, Cho H, Liang Y, Perrotti D, Branciamore S, Rockne R, Wu X, Ghoda L, Li L, Jin J, Chen J, Yu J, Caligiuri MA, Kuo YH, Boldin M, Su R, Swiderski P, Kortylewski M, Pirrotte P, Nguyen LXT, Marcucci G. Zhang B, et al. Among authors: nguyen lxt. Nat Commun. 2023 Sep 1;14(1):5325. doi: 10.1038/s41467-023-41167-z. Nat Commun. 2023. PMID: 37658085 Free PMC article.
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal.
Li Y, Xue M, Deng X, Dong L, Nguyen LXT, Ren L, Han L, Li C, Xue J, Zhao Z, Li W, Qing Y, Shen C, Tan B, Chen Z, Leung K, Wang K, Swaminathan S, Li L, Wunderlich M, Mulloy JC, Li X, Chen H, Zhang B, Horne D, Rosen ST, Marcucci G, Xu M, Li Z, Wei M, Tian J, Shen B, Su R, Chen J. Li Y, et al. Among authors: nguyen lxt. Cell Stem Cell. 2023 Aug 3;30(8):1072-1090.e10. doi: 10.1016/j.stem.2023.07.001. Cell Stem Cell. 2023. PMID: 37541212
Targeting miR-126 in Ph+ acute lymphoblastic leukemia.
Qiao J, Zhao D, Nguyen LXT, Chen F, Liang C, Estrella K, Ghoda LY, Heisterkamp N, Marcucci EC, Kuo YH, Marcucci G, Zhang B. Qiao J, et al. Among authors: nguyen lxt. Leukemia. 2023 Jul;37(7):1540-1544. doi: 10.1038/s41375-023-01933-w. Epub 2023 Jun 9. Leukemia. 2023. PMID: 37296274 Free PMC article. No abstract available.
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia.
Chen Z, Zhou K, Xue J, Small A, Xiao G, Nguyen LXT, Zhang Z, Prince E, Weng H, Huang H, Zhao Z, Qing Y, Shen C, Li W, Han L, Tan B, Su R, Qin H, Li Y, Wu D, Gu Z, Ngo VN, He X, Chao J, Leung K, Wang K, Dong L, Qin X, Cai Z, Sheng Y, Chen Y, Wu X, Zhang B, Shi Y, Marcucci G, Qian Z, Xu M, Müschen M, Chen J, Deng X. Chen Z, et al. Among authors: nguyen lxt. Sci Transl Med. 2023 Mar 29;15(689):eabq8513. doi: 10.1126/scitranslmed.abq8513. Epub 2023 Mar 29. Sci Transl Med. 2023. PMID: 36989375
26 results