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A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3.
Southam HM, Smith TW, Lyon RL, Liao C, Trevitt CR, Middlemiss LA, Cox FL, Chapman JA, El-Khamisy SF, Hippler M, Williamson MP, Henderson PJF, Poole RK. Southam HM, et al. Among authors: williamson mp. Redox Biol. 2018 Sep;18:114-123. doi: 10.1016/j.redox.2018.06.008. Epub 2018 Jun 30. Redox Biol. 2018. PMID: 30007887 Free PMC article.
Conformational exchange in the potassium channel blocker ShK.
Iwakawa N, Baxter NJ, Wai DCC, Fowler NJ, Morales RAV, Sugase K, Norton RS, Williamson MP. Iwakawa N, et al. Among authors: williamson mp. Sci Rep. 2019 Dec 17;9(1):19307. doi: 10.1038/s41598-019-55806-3. Sci Rep. 2019. PMID: 31848433 Free PMC article.
The accuracy of NMR protein structures in the Protein Data Bank.
Fowler NJ, Sljoka A, Williamson MP. Fowler NJ, et al. Among authors: williamson mp. Structure. 2021 Dec 2;29(12):1430-1439.e2. doi: 10.1016/j.str.2021.07.001. Epub 2021 Jul 30. Structure. 2021. PMID: 34331857 Free article.
CORM-3 induces DNA damage through Ru(II) binding to DNA.
Lyon RF, Southam HM, Trevitt CR, Liao C, El-Khamisy SF, Poole RK, Williamson MP. Lyon RF, et al. Among authors: williamson mp. Biochem J. 2022 Jul 15;479(13):1429-1439. doi: 10.1042/BCJ20220254. Biochem J. 2022. PMID: 35726678 Free PMC article.
Protein-protein interactions.
Williamson MP, Sutcliffe MJ. Williamson MP, et al. Biochem Soc Trans. 2010 Aug;38(4):875-8. doi: 10.1042/BST0380875. Biochem Soc Trans. 2010. PMID: 20658969 Review.
192 results