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The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus.
Joseph SB, Abrahams MR, Moeser M, Tyers L, Archin NM, Council OD, Sondgeroth A, Spielvogel E, Emery A, Zhou S, Doolabh D, Ismail SD, Karim SA, Margolis DM, Pond SK, Garrett N, Swanstrom R, Williamson C. Joseph SB, et al. Among authors: archin nm. PLoS Pathog. 2024 Feb 29;20(2):e1011974. doi: 10.1371/journal.ppat.1011974. eCollection 2024 Feb. PLoS Pathog. 2024. PMID: 38422171 Free PMC article.
Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells.
Anderson JA, Archin NM, Ince W, Parker D, Wiegand A, Coffin JM, Kuruc J, Eron J, Swanstrom R, Margolis DM. Anderson JA, et al. Among authors: archin nm. J Virol. 2011 May;85(10):5220-3. doi: 10.1128/JVI.00284-11. Epub 2011 Mar 2. J Virol. 2011. PMID: 21367910 Free PMC article.
96 results