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The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus.
Joseph SB, Abrahams MR, Moeser M, Tyers L, Archin NM, Council OD, Sondgeroth A, Spielvogel E, Emery A, Zhou S, Doolabh D, Ismail SD, Karim SA, Margolis DM, Pond SK, Garrett N, Swanstrom R, Williamson C. Joseph SB, et al. Among authors: karim sa. PLoS Pathog. 2024 Feb 29;20(2):e1011974. doi: 10.1371/journal.ppat.1011974. eCollection 2024 Feb. PLoS Pathog. 2024. PMID: 38422171 Free PMC article.
The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation.
Abrahams MR, Joseph SB, Garrett N, Tyers L, Moeser M, Archin N, Council OD, Matten D, Zhou S, Doolabh D, Anthony C, Goonetilleke N, Karim SA, Margolis DM, Pond SK, Williamson C, Swanstrom R. Abrahams MR, et al. Among authors: karim sa. Sci Transl Med. 2019 Oct 9;11(513):eaaw5589. doi: 10.1126/scitranslmed.aaw5589. Sci Transl Med. 2019. PMID: 31597754 Free PMC article.
Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.
Ping LH, Joseph SB, Anderson JA, Abrahams MR, Salazar-Gonzalez JF, Kincer LP, Treurnicht FK, Arney L, Ojeda S, Zhang M, Keys J, Potter EL, Chu H, Moore P, Salazar MG, Iyer S, Jabara C, Kirchherr J, Mapanje C, Ngandu N, Seoighe C, Hoffman I, Gao F, Tang Y, Labranche C, Lee B, Saville A, Vermeulen M, Fiscus S, Morris L, Karim SA, Haynes BF, Shaw GM, Korber BT, Hahn BH, Cohen MS, Montefiori D, Williamson C, Swanstrom R; CAPRISA Acute Infection Study and the Center for HIV-AIDS Vaccine Immunology Consortium. Ping LH, et al. Among authors: karim sa. J Virol. 2013 Jul;87(13):7218-33. doi: 10.1128/JVI.03577-12. Epub 2013 Apr 24. J Virol. 2013. PMID: 23616655 Free PMC article.
Short communication decreased incidence of dual infections in South african subtype C-infected women compared to a cohort ten years earlier.
Woodman Z, Mlisana K, Treurnicht F, Abrahams MR, Thebus R, Karim SA, Williamson C; Caprisa Acute Infection Study Team. Woodman Z, et al. Among authors: karim sa. AIDS Res Hum Retroviruses. 2011 Nov;27(11):1167-72. doi: 10.1089/aid.2010.0162. Epub 2011 Feb 9. AIDS Res Hum Retroviruses. 2011. PMID: 21198409 Free PMC article.
Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.
Wagh K, Bhattacharya T, Williamson C, Robles A, Bayne M, Garrity J, Rist M, Rademeyer C, Yoon H, Lapedes A, Gao H, Greene K, Louder MK, Kong R, Karim SA, Burton DR, Barouch DH, Nussenzweig MC, Mascola JR, Morris L, Montefiori DC, Korber B, Seaman MS. Wagh K, et al. Among authors: karim sa. PLoS Pathog. 2016 Mar 30;12(3):e1005520. doi: 10.1371/journal.ppat.1005520. eCollection 2016 Mar. PLoS Pathog. 2016. PMID: 27028935 Free PMC article.
Characterization and selection of HIV-1 subtype C isolates for use in vaccine development.
Williamson C, Morris L, Maughan MF, Ping LH, Dryga SA, Thomas R, Reap EA, Cilliers T, van Harmelen J, Pascual A, Ramjee G, Gray G, Johnston R, Karim SA, Swanstrom R. Williamson C, et al. Among authors: karim sa. AIDS Res Hum Retroviruses. 2003 Feb;19(2):133-44. doi: 10.1089/088922203762688649. AIDS Res Hum Retroviruses. 2003. PMID: 12639249
220 results