Hornung V - Search Results

1

Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production.

Harioudh MK, Perez J, Chong Z, Nair S, So L, McCormick KD, Ghosh A, Shao L, Srivastava R, Soveg F, Ebert TS, Atianand MK, Hornung V, Savan R, Diamond MS, Sarkar SN. Harioudh MK, et al. Among authors: hornung v. Immunity. 2024 Mar 12;57(3):446-461.e7. doi: 10.1016/j.immuni.2024.02.002. Epub 2024 Feb 28. Immunity. 2024. PMID: 38423012

2

Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor.

Zhu J, Zhang Y, Ghosh A, Cuevas RA, Forero A, Dhar J, Ibsen MS, Schmid-Burgk JL, Schmidt T, Ganapathiraju MK, Fujita T, Hartmann R, Barik S, Hornung V, Coyne CB, Sarkar SN. Zhu J, et al. Among authors: hornung v. Immunity. 2014 Jun 19;40(6):936-48. doi: 10.1016/j.immuni.2014.05.007. Epub 2014 Jun 12. Immunity. 2014. PMID: 24931123 Free PMC article.

3

MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I-MAVS-Independent IFN Induction.

Cuevas RA, Ghosh A, Wallerath C, Hornung V, Coyne CB, Sarkar SN. Cuevas RA, et al. Among authors: hornung v. J Immunol. 2016 May 1;196(9):3877-86. doi: 10.4049/jimmunol.1501359. Epub 2016 Mar 25. J Immunol. 2016. PMID: 27016603 Free PMC article.

4

Human Monocytes Engage an Alternative Inflammasome Pathway.

Gaidt MM, Ebert TS, Chauhan D, Schmidt T, Schmid-Burgk JL, Rapino F, Robertson AA, Cooper MA, Graf T, Hornung V. Gaidt MM, et al. Among authors: hornung v. Immunity. 2016 Apr 19;44(4):833-46. doi: 10.1016/j.immuni.2016.01.012. Epub 2016 Mar 29. Immunity. 2016. PMID: 27037191 Free article.

5

IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.

Shao L, Hou W, Scharping NE, Vendetti FP, Srivastava R, Roy CN, Menk AV, Wang Y, Chauvin JM, Karukonda P, Thorne SH, Hornung V, Zarour HM, Bakkenist CJ, Delgoffe GM, Sarkar SN. Shao L, et al. Among authors: hornung v. Cancer Immunol Res. 2019 Aug;7(8):1258-1266. doi: 10.1158/2326-6066.CIR-18-0711. Epub 2019 Jun 25. Cancer Immunol Res. 2019. PMID: 31239318 Free PMC article.

6

Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.

Ibsen MS, Gad HH, Andersen LL, Hornung V, Julkunen I, Sarkar SN, Hartmann R. Ibsen MS, et al. Among authors: hornung v. Nucleic Acids Res. 2015 May 26;43(10):5236-48. doi: 10.1093/nar/gkv389. Epub 2015 Apr 29. Nucleic Acids Res. 2015. PMID: 25925578 Free PMC article.

7

CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism.

Schmid-Burgk JL, Höning K, Ebert TS, Hornung V. Schmid-Burgk JL, et al. Among authors: hornung v. Nat Commun. 2016 Jul 28;7:12338. doi: 10.1038/ncomms12338. Nat Commun. 2016. PMID: 27465542 Free PMC article.

8

Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells.

Schmid-Burgk JL, Gaidt MM, Schmidt T, Ebert TS, Bartok E, Hornung V. Schmid-Burgk JL, et al. Among authors: hornung v. Eur J Immunol. 2015 Oct;45(10):2911-7. doi: 10.1002/eji.201545523. Epub 2015 Aug 6. Eur J Immunol. 2015. PMID: 26174085 Free article.

9

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.

Schmid-Burgk JL, Chauhan D, Schmidt T, Ebert TS, Reinhardt J, Endl E, Hornung V. Schmid-Burgk JL, et al. Among authors: hornung v. J Biol Chem. 2016 Jan 1;291(1):103-9. doi: 10.1074/jbc.C115.700492. Epub 2015 Nov 9. J Biol Chem. 2016. PMID: 26553871 Free PMC article.

10

Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth.

Ranjbar S, Haridas V, Nambu A, Jasenosky LD, Sadhukhan S, Ebert TS, Hornung V, Cassell GH, Falvo JV, Goldfeld AE. Ranjbar S, et al. Among authors: hornung v. iScience. 2019 Dec 20;22:299-313. doi: 10.1016/j.isci.2019.11.001. Epub 2019 Nov 6. iScience. 2019. PMID: 31805434 Free PMC article.

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