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An Insertion Within SIRPβ1 Shows a Dual Effect Over Alzheimer's Disease Cognitive Decline Altering the Microglial Response.
J Alzheimers Dis. 2024;98(2):601-618. doi: 10.3233/JAD-231150.
J Alzheimers Dis. 2024.
PMID: 38427484
Exposure to quasi-ultrafine particulate matter accelerates memory impairment and Alzheimer's disease-like neuropathology in the AppNL-G-F knock-in mouse model.
Kilian JG, Mejias-Ortega M, Hsu HW, Herman DA, Vidal J, Arechavala RJ, Renusch S, Dalal H, Hasen I, Ting A, Rodriguez-Ortiz CJ, Lim SL, Lin X, Vu J, Saito T, Saido TC, Kleinman MT, Kitazawa M.
Kilian JG, et al. Among authors: mejias ortega m.
Toxicol Sci. 2023 May 31;193(2):175-191. doi: 10.1093/toxsci/kfad036.
Toxicol Sci. 2023.
PMID: 37074955
Free PMC article.
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Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer's disease hippocampus.
Muñoz-Castro C, Mejias-Ortega M, Sanchez-Mejias E, Navarro V, Trujillo-Estrada L, Jimenez S, Garcia-Leon JA, Fernandez-Valenzuela JJ, Sanchez-Mico MV, Romero-Molina C, Moreno-Gonzalez I, Baglietto-Vargas D, Vizuete M, Gutierrez A, Vitorica J.
Muñoz-Castro C, et al. Among authors: mejias ortega m.
Acta Neuropathol Commun. 2023 Feb 28;11(1):31. doi: 10.1186/s40478-023-01530-z.
Acta Neuropathol Commun. 2023.
PMID: 36855152
Free PMC article.
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Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats.
Rodriguez-Ortiz CJ, Thorwald MA, Rodriguez R, Mejias-Ortega M, Kieu Z, Maitra N, Hawkins C, Valenzuela J, Peng M, Nishiyama A, Ortiz RM, Kitazawa M.
Rodriguez-Ortiz CJ, et al. Among authors: mejias ortega m.
Clin Exp Pharmacol Physiol. 2023 Mar;50(3):228-237. doi: 10.1111/1440-1681.13738. Epub 2022 Dec 4.
Clin Exp Pharmacol Physiol. 2023.
PMID: 36398458
Free PMC article.
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Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis.
Sanchez-Varo R, Mejias-Ortega M, Fernandez-Valenzuela JJ, Nuñez-Diaz C, Caceres-Palomo L, Vegas-Gomez L, Sanchez-Mejias E, Trujillo-Estrada L, Garcia-Leon JA, Moreno-Gonzalez I, Vizuete M, Vitorica J, Baglietto-Vargas D, Gutierrez A.
Sanchez-Varo R, et al. Among authors: mejias ortega m.
Int J Mol Sci. 2022 May 12;23(10):5404. doi: 10.3390/ijms23105404.
Int J Mol Sci. 2022.
PMID: 35628216
Free PMC article.
Review.
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Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis.
Sanchez-Varo R, Sanchez-Mejias E, Fernandez-Valenzuela JJ, De Castro V, Mejias-Ortega M, Gomez-Arboledas A, Jimenez S, Sanchez-Mico MV, Trujillo-Estrada L, Moreno-Gonzalez I, Baglietto-Vargas D, Vizuete M, Davila JC, Vitorica J, Gutierrez A.
Sanchez-Varo R, et al. Among authors: mejias ortega m.
Front Neurosci. 2021 Nov 4;15:752594. doi: 10.3389/fnins.2021.752594. eCollection 2021.
Front Neurosci. 2021.
PMID: 34803589
Free PMC article.
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Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer's Disease.
Garcia-Leon JA, Caceres-Palomo L, Sanchez-Mejias E, Mejias-Ortega M, Nuñez-Diaz C, Fernandez-Valenzuela JJ, Sanchez-Varo R, Davila JC, Vitorica J, Gutierrez A.
Garcia-Leon JA, et al. Among authors: mejias ortega m.
Int J Mol Sci. 2020 Sep 18;21(18):6867. doi: 10.3390/ijms21186867.
Int J Mol Sci. 2020.
PMID: 32962164
Free PMC article.
Review.
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Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients.
Sanchez-Mejias E, Nuñez-Diaz C, Sanchez-Varo R, Gomez-Arboledas A, Garcia-Leon JA, Fernandez-Valenzuela JJ, Mejias-Ortega M, Trujillo-Estrada L, Baglietto-Vargas D, Moreno-Gonzalez I, Davila JC, Vitorica J, Gutierrez A.
Sanchez-Mejias E, et al. Among authors: mejias ortega m.
Brain Pathol. 2020 Mar;30(2):345-363. doi: 10.1111/bpa.12785. Epub 2019 Oct 9.
Brain Pathol. 2020.
PMID: 31491047
Free PMC article.
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