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Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes.
Chaudhary N, Newby AN, Arral ML, Yerneni SS, LoPresti ST, Doerfler R, Petersen DMS, Montoya C, Kim JS, Fox B, Coon T, Malaney A, Sadovsky Y, Whitehead KA. Chaudhary N, et al. Among authors: sadovsky y. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307810121. doi: 10.1073/pnas.2307810121. Epub 2024 Mar 4. Proc Natl Acad Sci U S A. 2024. PMID: 38437545 Free PMC article.
PLA2G6 guards placental trophoblasts against ferroptotic injury.
Beharier O, Tyurin VA, Goff JP, Guerrero-Santoro J, Kajiwara K, Chu T, Tyurina YY, St Croix CM, Wallace CT, Parry S, Parks WT, Kagan VE, Sadovsky Y. Beharier O, et al. Among authors: sadovsky y. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27319-27328. doi: 10.1073/pnas.2009201117. Epub 2020 Oct 21. Proc Natl Acad Sci U S A. 2020. PMID: 33087576 Free PMC article.
Human placental trophoblasts confer viral resistance to recipient cells.
Delorme-Axford E, Donker RB, Mouillet JF, Chu T, Bayer A, Ouyang Y, Wang T, Stolz DB, Sarkar SN, Morelli AE, Sadovsky Y, Coyne CB. Delorme-Axford E, et al. Among authors: sadovsky y. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12048-53. doi: 10.1073/pnas.1304718110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818581 Free PMC article.
Isolation of exosomes from whole blood by integrating acoustics and microfluidics.
Wu M, Ouyang Y, Wang Z, Zhang R, Huang PH, Chen C, Li H, Li P, Quinn D, Dao M, Suresh S, Sadovsky Y, Huang TJ. Wu M, et al. Among authors: sadovsky y. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10584-10589. doi: 10.1073/pnas.1709210114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923936 Free PMC article.
Formation and size distribution of self-assembled vesicles.
Huang C, Quinn D, Sadovsky Y, Suresh S, Hsia KJ. Huang C, et al. Among authors: sadovsky y. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2910-2915. doi: 10.1073/pnas.1702065114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265065 Free PMC article. Review.
Vulnerability of primitive human placental trophoblast to Zika virus.
Sheridan MA, Yunusov D, Balaraman V, Alexenko AP, Yabe S, Verjovski-Almeida S, Schust DJ, Franz AW, Sadovsky Y, Ezashi T, Roberts RM. Sheridan MA, et al. Among authors: sadovsky y. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1587-E1596. doi: 10.1073/pnas.1616097114. Epub 2017 Feb 13. Proc Natl Acad Sci U S A. 2017. PMID: 28193876 Free PMC article.
232 results