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B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans.
Wang AA, Luessi F, Neziraj T, Pössnecker E, Zuo M, Engel S, Hanuscheck N, Florescu A, Bugbee E, Ma XI, Rana F, Lee D, Ward LA, Kuhle J, Himbert J, Schraad M, van Puijenbroek E, Klein C, Urich E, Ramaglia V, Pröbstel AK, Zipp F, Gommerman JL. Wang AA, et al. Among authors: kuhle j. Sci Transl Med. 2024 Mar 6;16(737):eadi0295. doi: 10.1126/scitranslmed.adi0295. Epub 2024 Mar 6. Sci Transl Med. 2024. PMID: 38446903
Multiple Sclerosis and Antibodies against KIR4.1.
Pröbstel AK, Kuhle J, Lecourt AC, Vock I, Sanderson NS, Kappos L, Derfuss T. Pröbstel AK, et al. Among authors: kuhle j. N Engl J Med. 2016 Apr 14;374(15):1496-8. doi: 10.1056/NEJMc1507131. N Engl J Med. 2016. PMID: 27074084 No abstract available.
Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis.
Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. Pröbstel AK, et al. Among authors: kuhle j. Sci Immunol. 2020 Nov 20;5(53):eabc7191. doi: 10.1126/sciimmunol.abc7191. Sci Immunol. 2020. PMID: 33219152 Free PMC article.
Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder: A Retrospective, Cross-sectional Analysis.
Müller J, Sinnecker T, Wendebourg MJ, Schläger R, Kuhle J, Schädelin S, Benkert P, Derfuss T, Cattin P, Jud C, Spiess F, Amann M, Lincke T, Barakovic M, Cagol A, Tsagkas C, Parmar K, Pröbstel AK, Reimann S, Asseyer S, Duchow A, Brandt A, Ruprecht K, Hadjikhani N, Fukumoto S, Watanabe M, Masaki K, Matsushita T, Isobe N, Kira JI, Kappos L, Würfel J, Granziera C, Paul F, Yaldizli Ö. Müller J, et al. Among authors: kuhle j. Neurol Neuroimmunol Neuroinflamm. 2022 Feb 25;9(3):e1147. doi: 10.1212/NXI.0000000000001147. Print 2022 May. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 35217580 Free PMC article.
Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study.
Etter MM, Martins TA, Kulsvehagen L, Pössnecker E, Duchemin W, Hogan S, Sanabria-Diaz G, Müller J, Chiappini A, Rychen J, Eberhard N, Guzman R, Mariani L, Melie-Garcia L, Keller E, Jelcic I, Pargger H, Siegemund M, Kuhle J, Oechtering J, Eich C, Tzankov A, Matter MS, Uzun S, Yaldizli Ö, Lieb JM, Psychogios MN, Leuzinger K, Hirsch HH, Granziera C, Pröbstel AK, Hutter G. Etter MM, et al. Among authors: kuhle j. Nat Commun. 2022 Nov 9;13(1):6777. doi: 10.1038/s41467-022-34068-0. Nat Commun. 2022. PMID: 36351919 Free PMC article.
Anterior horn atrophy in the cervical spinal cord: A new biomarker in progressive multiple sclerosis.
Tsagkas C, Huck-Horvath A, Cagol A, Haas T, Barakovic M, Amann M, Ruberte E, Melie-Garcia L, Weigel M, Pezold S, Schlaeger R, Kuhle J, Sprenger T, Kappos L, Bieri O, Cattin P, Granziera C, Parmar K. Tsagkas C, et al. Among authors: kuhle j. Mult Scler. 2023 May;29(6):702-718. doi: 10.1177/13524585221139152. Epub 2022 Dec 22. Mult Scler. 2023. PMID: 36550626
Real-world evaluation of ocrelizumab in multiple sclerosis: A systematic review.
Montalban X, Matthews PM, Simpson A, Petrie JL, Sammon C, Ramagopalan S, Disanto G, Kuhle J. Montalban X, et al. Among authors: kuhle j. Ann Clin Transl Neurol. 2023 Mar;10(3):302-311. doi: 10.1002/acn3.51732. Epub 2023 Feb 2. Ann Clin Transl Neurol. 2023. PMID: 36728340 Free PMC article. Review.
451 results