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Page 1
Universal recording of immune cell interactions in vivo.
Nakandakari-Higa S, Walker S, Canesso MCC, van der Heide V, Chudnovskiy A, Kim DY, Jacobsen JT, Parsa R, Bilanovic J, Parigi SM, Fiedorczuk K, Fuchs E, Bilate AM, Pasqual G, Mucida D, Kamphorst AO, Pritykin Y, Victora GD. Nakandakari-Higa S, et al. Among authors: kamphorst ao. Nature. 2024 Mar;627(8003):399-406. doi: 10.1038/s41586-024-07134-4. Epub 2024 Mar 6. Nature. 2024. PMID: 38448581
Advancing beyond the twists and turns of T cell exhaustion in cancer.
van der Heide V, Humblin E, Vaidya A, Kamphorst AO. van der Heide V, et al. Among authors: kamphorst ao. Sci Transl Med. 2022 Nov 9;14(670):eabo4997. doi: 10.1126/scitranslmed.abo4997. Epub 2022 Nov 9. Sci Transl Med. 2022. PMID: 36350991 Free PMC article. Review.
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1+ PD-1+ CD8 T cells.
Humblin E, Korpas I, Lu J, Filipescu D, van der Heide V, Goldstein S, Vaidya A, Soares-Schanoski A, Casati B, Selvan ME, Gümüş ZH, Wieland A, Corrado M, Cohen-Gould L, Bernstein E, Homann D, Chipuk J, Kamphorst AO. Humblin E, et al. Among authors: kamphorst ao. Sci Immunol. 2023 Aug 4;8(86):eadg0878. doi: 10.1126/sciimmunol.adg0878. Epub 2023 Aug 25. Sci Immunol. 2023. PMID: 37624910 Free PMC article.
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.
Jansen CS, Prokhnevska N, Master VA, Sanda MG, Carlisle JW, Bilen MA, Cardenas M, Wilkinson S, Lake R, Sowalsky AG, Valanparambil RM, Hudson WH, McGuire D, Melnick K, Khan AI, Kim K, Chang YM, Kim A, Filson CP, Alemozaffar M, Osunkoya AO, Mullane P, Ellis C, Akondy R, Im SJ, Kamphorst AO, Reyes A, Liu Y, Kissick H. Jansen CS, et al. Among authors: kamphorst ao. Nature. 2019 Dec;576(7787):465-470. doi: 10.1038/s41586-019-1836-5. Epub 2019 Dec 11. Nature. 2019. PMID: 31827286 Free PMC article.
Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection.
Guermonprez P, Helft J, Claser C, Deroubaix S, Karanje H, Gazumyan A, Darasse-Jèze G, Telerman SB, Breton G, Schreiber HA, Frias-Staheli N, Billerbeck E, Dorner M, Rice CM, Ploss A, Klein F, Swiecki M, Colonna M, Kamphorst AO, Meredith M, Niec R, Takacs C, Mikhail F, Hari A, Bosque D, Eisenreich T, Merad M, Shi Y, Ginhoux F, Rénia L, Urban BC, Nussenzweig MC. Guermonprez P, et al. Among authors: kamphorst ao. Nat Med. 2013 Jun;19(6):730-8. doi: 10.1038/nm.3197. Epub 2013 May 19. Nat Med. 2013. PMID: 23685841 Free PMC article.
MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping.
Filipescu D, Carcamo S, Agarwal A, Tung N, Humblin É, Goldberg MS, Vyas NS, Beaumont KG, Demircioglu D, Sridhar S, Ghiraldini FG, Capparelli C, Aplin AE, Salmon H, Sebra R, Kamphorst AO, Merad M, Hasson D, Bernstein E. Filipescu D, et al. Among authors: kamphorst ao. Nat Cell Biol. 2023 Sep;25(9):1332-1345. doi: 10.1038/s41556-023-01208-7. Epub 2023 Aug 21. Nat Cell Biol. 2023. PMID: 37605008 Free PMC article.
Differential antigen processing by dendritic cell subsets in vivo.
Dudziak D, Kamphorst AO, Heidkamp GF, Buchholz VR, Trumpfheller C, Yamazaki S, Cheong C, Liu K, Lee HW, Park CG, Steinman RM, Nussenzweig MC. Dudziak D, et al. Among authors: kamphorst ao. Science. 2007 Jan 5;315(5808):107-11. doi: 10.1126/science.1136080. Science. 2007. PMID: 17204652 Free article.
Functional impairment of "helpless" CD8 + memory T cells is transient and driven by prolonged but finite cognate antigen presentation.
van der Heide V, Davenport B, Cubitt B, Roudko V, Choo D, Humblin E, Jhun K, Angeliadis K, Dawson T, Furtado G, Kamphorst A, Ahmed R, de la Torre JC, Homann D. van der Heide V, et al. bioRxiv [Preprint]. 2024 Jan 26:2024.01.22.576725. doi: 10.1101/2024.01.22.576725. bioRxiv. 2024. PMID: 38328184 Free PMC article. Preprint.
45 results