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Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria.
Foss S, Sakya SA, Aguinagalde L, Lustig M, Shaughnessy J, Cruz AR, Scheepmaker L, Mathiesen L, Ruso-Julve F, Anthi AK, Gjølberg TT, Mester S, Bern M, Evers M, Bratlie DB, Michaelsen TE, Schlothauer T, Sok D, Bhattacharya J, Leusen J, Valerius T, Ram S, Rooijakkers SHM, Sandlie I, Andersen JT. Foss S, et al. Among authors: gjolberg tt. Nat Commun. 2024 Mar 7;15(1):2007. doi: 10.1038/s41467-024-46321-9. Nat Commun. 2024. PMID: 38453922 Free PMC article.
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics.
Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT. Bern M, et al. Among authors: gjolberg tt. Sci Transl Med. 2020 Oct 14;12(565):eabb0580. doi: 10.1126/scitranslmed.abb0580. Sci Transl Med. 2020. PMID: 33055243
Antibody blockade of Jagged1 attenuates choroidal neovascularization.
Gjølberg TT, Wik JA, Johannessen H, Krüger S, Bassi N, Christopoulos PF, Bern M, Foss S, Petrovski G, Moe MC, Haraldsen G, Fosse JH, Skålhegg BS, Andersen JT, Sundlisæter E. Gjølberg TT, et al. Nat Commun. 2023 May 30;14(1):3109. doi: 10.1038/s41467-023-38563-w. Nat Commun. 2023. PMID: 37253747 Free PMC article.
A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.
Benjakul S, Anthi AK, Kolderup A, Vaysburd M, Lode HE, Mallery D, Fossum E, Vikse EL, Albecka A, Ianevski A, Kainov D, Karlsen KF, Sakya SA, Nyquist-Andersen M, Gjølberg TT, Moe MC, Bjørås M, Sandlie I, James LC, Andersen JT. Benjakul S, et al. Among authors: gjolberg tt. PNAS Nexus. 2023 Nov 28;2(12):pgad403. doi: 10.1093/pnasnexus/pgad403. eCollection 2023 Dec. PNAS Nexus. 2023. PMID: 38077689 Free PMC article.
Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties.
Jørstad ØK, Foss S, Gjølberg TT, Mester S, Nyquist-Andersen M, Sivertsen MS, Fossum D, Gleditsch E, Moe MC, Andersen JT. Jørstad ØK, et al. Among authors: gjolberg tt. Int J Retina Vitreous. 2023 Nov 7;9(1):65. doi: 10.1186/s40942-023-00507-3. Int J Retina Vitreous. 2023. PMID: 37936232 Free PMC article.
Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases.
Christopoulos PF, Gjølberg TT, Krüger S, Haraldsen G, Andersen JT, Sundlisæter E. Christopoulos PF, et al. Among authors: gjolberg tt. Front Immunol. 2021 Apr 12;12:668207. doi: 10.3389/fimmu.2021.668207. eCollection 2021. Front Immunol. 2021. PMID: 33912195 Free PMC article. Review.
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