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CDK-independent role of D-type cyclins in regulating DNA mismatch repair.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M. Rona G, et al. Among authors: keegan s. Mol Cell. 2024 Apr 4;84(7):1224-1242.e13. doi: 10.1016/j.molcel.2024.02.010. Epub 2024 Mar 7. Mol Cell. 2024. PMID: 38458201 Free article.
D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M. Rona G, et al. Among authors: keegan s. bioRxiv [Preprint]. 2024 Jan 13:2024.01.12.575420. doi: 10.1101/2024.01.12.575420. bioRxiv. 2024. PMID: 38260436 Free PMC article. Updated. Preprint.
CRL4AMBRA1 is a master regulator of D-type cyclins.
Simoneschi D, Rona G, Zhou N, Jeong YT, Jiang S, Milletti G, Arbini AA, O'Sullivan A, Wang AA, Nithikasem S, Keegan S, Siu Y, Cianfanelli V, Maiani E, Nazio F, Cecconi F, Boccalatte F, Fenyö D, Jones DR, Busino L, Pagano M. Simoneschi D, et al. Among authors: keegan s. Nature. 2021 Apr;592(7856):789-793. doi: 10.1038/s41586-021-03445-y. Epub 2021 Apr 14. Nature. 2021. PMID: 33854235 Free PMC article.
The ULK1-FBXW5-SEC23B nexus controls autophagy.
Jeong YT, Simoneschi D, Keegan S, Melville D, Adler NS, Saraf A, Florens L, Washburn MP, Cavasotto CN, Fenyö D, Cuervo AM, Rossi M, Pagano M. Jeong YT, et al. Among authors: keegan s. Elife. 2018 Dec 31;7:e42253. doi: 10.7554/eLife.42253. Elife. 2018. PMID: 30596474 Free PMC article.
Dissecting the Structural Dynamics of the Nuclear Pore Complex.
Hakhverdyan Z, Molloy KR, Keegan S, Herricks T, Lepore DM, Munson M, Subbotin RI, Fenyö D, Aitchison JD, Fernandez-Martinez J, Chait BT, Rout MP. Hakhverdyan Z, et al. Among authors: keegan s. Mol Cell. 2021 Jan 7;81(1):153-165.e7. doi: 10.1016/j.molcel.2020.11.032. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333016 Free PMC article.
Single Molecule Localization Microscopy of DNA Damage Response Pathways in Cancer.
Whelan DR, Yin Y, Bermudez-Hernandez K, Keegan S, Fenyö D, Rothenberg E. Whelan DR, et al. Among authors: keegan s. Microsc Microanal. 2016 Jul;22(Suppl 3):1016-1017. doi: 10.1017/S1431927616005924. Epub 2016 Jul 25. Microsc Microanal. 2016. PMID: 28239291 Free PMC article. No abstract available.
92 results