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Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2.
Schmitt L, Lechtenberg I, Drießen D, Flores-Romero H, Skowron MA, Sekeres M, Hoppe J, Krings KS, Llewellyn TR, Peter C, Stork B, Qin N, Bhatia S, Nettersheim D, Fritz G, García-Sáez AJ, Müller TJJ, Wesselborg S. Schmitt L, et al. Among authors: garcia saez aj. Cell Death Discov. 2024 Mar 9;10(1):125. doi: 10.1038/s41420-024-01901-y. Cell Death Discov. 2024. PMID: 38461295 Free PMC article.
The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane.
Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B. Böhler P, et al. Cell Death Dis. 2018 Feb 19;9(3):286. doi: 10.1038/s41419-018-0312-8. Cell Death Dis. 2018. PMID: 29459714 Free PMC article.
Lipids glue BAK dimers together.
Flores-Romero H, García-Sáez AJ. Flores-Romero H, et al. Nat Struct Mol Biol. 2020 Nov;27(11):1003-1004. doi: 10.1038/s41594-020-00516-y. Nat Struct Mol Biol. 2020. PMID: 32994578 No abstract available.
The Mysteries around the BCL-2 Family Member BOK.
Shalaby R, Flores-Romero H, García-Sáez AJ. Shalaby R, et al. Biomolecules. 2020 Dec 4;10(12):1638. doi: 10.3390/biom10121638. Biomolecules. 2020. PMID: 33291826 Free PMC article. Review.
Pore formation in regulated cell death.
Flores-Romero H, Ros U, Garcia-Saez AJ. Flores-Romero H, et al. EMBO J. 2020 Dec 1;39(23):e105753. doi: 10.15252/embj.2020105753. Epub 2020 Oct 30. EMBO J. 2020. PMID: 33124082 Free PMC article. Review.
MAVS-induced mitochondrial membrane remodeling.
Flores-Romero H, García-Sáez AJ. Flores-Romero H, et al. FEBS J. 2019 Apr;286(8):1540-1542. doi: 10.1111/febs.14822. Epub 2019 Apr 8. FEBS J. 2019. PMID: 30957952 Free article.
The Incomplete Puzzle of the BCL2 Proteins.
Flores-Romero H, García-Sáez AJ. Flores-Romero H, et al. Cells. 2019 Sep 29;8(10):1176. doi: 10.3390/cells8101176. Cells. 2019. PMID: 31569576 Free PMC article. Review.
A lipid perspective on regulated cell death.
Flores-Romero H, Ros U, García-Sáez AJ. Flores-Romero H, et al. Int Rev Cell Mol Biol. 2020;351:197-236. doi: 10.1016/bs.ircmb.2019.11.004. Epub 2019 Dec 18. Int Rev Cell Mol Biol. 2020. PMID: 32247580 Review.
130 results