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Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2.
Schmitt L, Lechtenberg I, Drießen D, Flores-Romero H, Skowron MA, Sekeres M, Hoppe J, Krings KS, Llewellyn TR, Peter C, Stork B, Qin N, Bhatia S, Nettersheim D, Fritz G, García-Sáez AJ, Müller TJJ, Wesselborg S. Schmitt L, et al. Among authors: stork b. Cell Death Discov. 2024 Mar 9;10(1):125. doi: 10.1038/s41420-024-01901-y. Cell Death Discov. 2024. PMID: 38461295 Free PMC article.
The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane.
Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B. Böhler P, et al. Among authors: stork b. Cell Death Dis. 2018 Feb 19;9(3):286. doi: 10.1038/s41419-018-0312-8. Cell Death Dis. 2018. PMID: 29459714 Free PMC article.
Novel meriolin derivatives as rapid apoptosis inducers.
Drießen D, Stuhldreier F, Frank A, Stark H, Wesselborg S, Stork B, Müller TJJ. Drießen D, et al. Among authors: stork b. Bioorg Med Chem. 2019 Aug 1;27(15):3463-3468. doi: 10.1016/j.bmc.2019.06.029. Epub 2019 Jun 19. Bioorg Med Chem. 2019. PMID: 31248707
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism.
Stuhldreier F, Schmitt L, Lenz T, Hinxlage I, Zimmermann M, Wollnitzke P, Schliehe-Diecks J, Liu Y, Jäger P, Geyh S, Teusch N, Peter C, Bhatia S, Haas R, Levkau B, Reichert AS, Stühler K, Proksch P, Stork B, Wesselborg S. Stuhldreier F, et al. Among authors: stork b. Cell Death Dis. 2022 Nov 8;13(11):938. doi: 10.1038/s41419-022-05356-w. Cell Death Dis. 2022. PMID: 36347842 Free PMC article.
Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex.
Schlütermann D, Skowron MA, Berleth N, Böhler P, Deitersen J, Stuhldreier F, Wallot-Hieke N, Wu W, Peter C, Hoffmann MJ, Niegisch G, Stork B. Schlütermann D, et al. Among authors: stork b. Urol Oncol. 2018 Apr;36(4):160.e1-160.e13. doi: 10.1016/j.urolonc.2017.11.021. Epub 2017 Dec 21. Urol Oncol. 2018. PMID: 29276062 Free article.
Phomoxanthone A--From Mangrove Forests to Anticancer Therapy.
Frank M, Niemann H, Böhler P, Stork B, Wesselborg S, Lin W, Proksch P. Frank M, et al. Among authors: stork b. Curr Med Chem. 2015;22(30):3523-32. doi: 10.2174/0929867322666150716115300. Curr Med Chem. 2015. PMID: 26179997 Review.
Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells.
Sun Y, Berleth N, Wu W, Schlütermann D, Deitersen J, Stuhldreier F, Berning L, Friedrich A, Akgün S, Mendiburo MJ, Wesselborg S, Conrad M, Berndt C, Stork B. Sun Y, et al. Among authors: stork b. Cell Death Dis. 2021 Oct 29;12(11):1028. doi: 10.1038/s41419-021-04306-2. Cell Death Dis. 2021. PMID: 34716292 Free PMC article.
104 results