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Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 ( Abhd2 ) as an enzyme that metabolizes phosphatidylcholine and cardiolipin.
Price TR, Stapleton DS, Schueler KL, Norris MK, Parks BW, Yandell BS, Churchill GA, Holland WL, Keller MP, Attie AD. Price TR, et al. Among authors: keller mp. bioRxiv [Preprint]. 2023 Mar 24:2023.03.23.533902. doi: 10.1101/2023.03.23.533902. bioRxiv. 2023. PMID: 36993241 Free PMC article. Updated. Preprint.
Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.
Zhang Q, Linke V, Overmyer KA, Traeger LL, Kasahara K, Miller IJ, Manson DE, Polaske TJ, Kerby RL, Kemis JH, Trujillo EA, Reddy TR, Russell JD, Schueler KL, Stapleton DS, Rabaglia ME, Seldin M, Gatti DM, Keele GR, Pham DT, Gerdt JP, Vivas EI, Lusis AJ, Keller MP, Churchill GA, Blackwell HE, Broman KW, Attie AD, Coon JJ, Rey FE. Zhang Q, et al. Among authors: keller mp. Nat Microbiol. 2023 Mar;8(3):424-440. doi: 10.1038/s41564-023-01326-w. Epub 2023 Feb 9. Nat Microbiol. 2023. PMID: 36759753 Free PMC article.
Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy.
Niemi NM, Serrano LR, Muehlbauer LK, Balnis C, Kozul KL, Rashan EH, Shishkova E, Schueler KL, Keller MP, Attie AD, Pagan J, Coon JJ, Pagliarini DJ. Niemi NM, et al. Among authors: keller mp. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.530351. doi: 10.1101/2023.02.28.530351. bioRxiv. 2023. PMID: 36909604 Free PMC article. Updated. Preprint.
Genetic determinants of gut microbiota composition and bile acid profiles in mice.
Kemis JH, Linke V, Barrett KL, Boehm FJ, Traeger LL, Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Churchill GA, Amador-Noguez D, Russell JD, Yandell BS, Broman KW, Coon JJ, Attie AD, Rey FE. Kemis JH, et al. Among authors: keller mp. PLoS Genet. 2019 Aug 29;15(8):e1008073. doi: 10.1371/journal.pgen.1008073. eCollection 2019 Aug. PLoS Genet. 2019. PMID: 31465442 Free PMC article.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. Among authors: keller mp. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
Heme biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue.
Duerre DJ, Hansen JK, John S, Jen A, Carrillo N, Bui H, Bao Y, Fabregat M, Overmeyer K, Shishkova E, Keller MP, Anderson RA, Cryns VL, Attie AD, Coon JJ, Fan J, Galmozzi A. Duerre DJ, et al. Among authors: keller mp. bioRxiv [Preprint]. 2023 Nov 28:2023.11.28.568893. doi: 10.1101/2023.11.28.568893. bioRxiv. 2023. PMID: 38076785 Free PMC article. Preprint.
126 results